484686-94-4

Upstream product

• 385766-38-1 ethyl 2-methyl-5-[4-O-(4-methylphenylsulfonyl)-D-arabino-tetritol-1-yl]furan-3-carboxylate 
• 3351-43-7 ethyl 2-methyl-5-(D-arabino-tetritol-1-yl)furan-3-carboxylate 
• 98-59-9 p-toluenesulfonyl chloride 
• 484686-90-0 ethyl 5-((1SR,2R,3R)-1-chloro-2,3-dihydroxy-4-{[(4-methylphenyl)sulfonyl]oxy}butyl)-2-methylfuran-3-carboxylate 

Downstream Products

• 637743-02-3 5-{(2S,3S,4R)-3,4-dihydroxy-1-[(phenylmethoxy)carbonyl]pyrrolidin-2-yl}-2-methylfuran-3-carboxylic acid 
• 385766-44-9 5-{(2R,3S,4R)-3,4-dihydroxy-1-[(phenylmethoxy)carbonyl]pyrrolidin-2-yl}-2-methylfuran-3-carboxylic acid 
• 385766-45-0 (2R,3S,4R)-2-[4-(hydroxymethyl)-5-methylfuran-2-yl]pyrrolidine-3,4-diol 

Relevant academic research and scientific papers

Synthesis of [(2S,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]-5-methylfuran-4-carboxylic acid derivatives: New leads as selective β-galactosidase inhibitors

The preparation of [(2S,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]furan derivatives in a stereoselective route starting from D-glucose and ethyl acetoacetate is presented. Ethyl ester (6), N,N-diethylamide (7) and N-isopropylamide (8) have been tested towards 2