4847-47-6

Upstream product

• 64-17-5 ethanol 
• 1823-99-0 3-amino-3-phenylacrylonitrile 
• 542-14-3 aniline acetate 
• 935-02-4 3-Phenyl-2-propynonitrile 
• 62-53-3 aniline 
• 4492-01-7 1,3-diphenyl-1H-pyrazole 
• 1270-67-3 4-amino-2,3-diphenylthiazolium chloride 
• 614-16-4 Benzoylacetonitrile 
• 70801-58-0 2-Cyano-3-phenyl-4H-benzo<1,4>thiazine 

Downstream Products

• 614-16-4 Benzoylacetonitrile 
• 62-53-3 aniline 
• 117266-86-1 4-cyano-1,5-diphenyl-3-ethoxy-3-hydroxy-pyrrole-2-one 
• 51072-85-6 2-phenyl-1H-indole-3-carbonitrile 
• 93-98-1 N-phenyl benzoyl amide 
• 59393-45-2 3-phenyl-2-quinoxalinecarbonitrile 
• 72694-08-7 (Z)-2-Cyano-3-phenyl-3-phenylamino-dithioacrylic acid ethyl ester 
• 117266-85-0 4-cyano-1,5-diphenyl-pyrrole-2,3-dione 

Relevant academic research and scientific papers

Cobaloxime Catalysis for Enamine Phosphorylation with Hydrogen Evolution

Direct phosphorylation of enamine and enamide with hydrogen evolution was realized via cobaloxime catalysis under visible-light irradiation. Control experiments and spectroscopic studies demonstrated a reductive quenching pathway of cobaloxime catalyst to produce phosphinoyl radical, which underwent cross-coupling with various enamines (and enamides) to give diverse β-phosphinoyl products in good to excellent yields. More interestingly, Z/E mixture of acyclic enamines could convert into single Z-products with good reactivity.

PIDA-mediated oxidative C-C bond formation: Novel synthesis of indoles from n-aryl enamines

A variety of functionalized indoles were synthesized from N-aryl enamines via PIDA-mediated oxidative carbon-carbon bond formation. The features of the present reaction include facilitative preparation of substrates 2, good functional group tolerance, and mild reaction conditions without transition metals.

PHOTOCHEMICAL AND THERMAL REACTIONS OF HETEROCYCLES. PART 5. PRODUCTS VIA TRANSIENT QUASIANTIAROMATIC AZETINE INTERMEDIATES GENERATED BY DESULPHURISATION OF PHOTOCHEMICAL INTERMEDIATES FROM A THIAZOLIUM-4-OLATE AND 4-AMINOTHIAZOLIUM SALTS

Irradiation of the mesoionic triphenylthiazolium-4-olate (3) in the presence of tributylphosphine gave the quinolinone (7).This result was interpreted as arising via desulphurisation of the bicyclic intermediate (4) to the azetone (5), followed by its isomerisation to the ketene (6) and internal trapping.Similar irradiation of the 4-aminothiazolium salts (15) gave enamino nitriles (17) and benzoylacetonitrile (16).They are probably formed by isomerisation and hydration of the hitherto unknown quasiantiaromatic 2-imino-1,2-dihydroazete intermediates (20), which in turn are generated by desulphurisation of the bicyclic photochemical intermediates (19).