4855-62-3

Basic information

• Product Name: 4-bromo-2,5-dichlorophenyl dimethyl phosphate
• Synonyms: 4-Brom-2,5-dichlorphenyl-dimethylphosphat; 4-Bromo-2,5-dichlorophenyl dimethyl phosphate; Phosphate de 4-bromo-2,5-dichlorophényle et de diméthyle; phosphoric acid, 4-bromo-2,5-dichlorophenyl dimethyl ester
• CAS NO: 4855-62-3
• Molecular Formula: C₈H₈BrCl₂O₄P
• Molecular Weight: 349.9305
• Mol File: 4855-62-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 342.1°C at 760 mmHg
• Flash Point: 160.7°C
• Density: 1.691g/cm³
• Vapor Pressure: 0.000152mmHg at 25°C
• Refractive Index: 1.544
• CAS DataBase Reference: 4-bromo-2,5-dichlorophenyl dimethyl phosphate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2,5-dichlorophenyl dimethyl phosphate(4855-62-3)
• EPA Substance Registry System: 4-bromo-2,5-dichlorophenyl dimethyl phosphate(4855-62-3)

Safety Data

• Hazardous Substances Data: 4855-62-3(Hazardous Substances Data)

Upstream product

• 2104-96-3 bromophos methyl 

Relevant articles and documents

Oxidation of organophosphorus pesticides for the sensitive detection by a cholinesterase-based biosensor

A potentiometric flow injection-type biosensor developed in our laboratory was used for the determination of organophosphorus pesticides (OPs). The principle of the biosensor is that the degree of inhibition of a sensor enzyme by an OP is dependent on the concentration of the pesticide. The sensor system consisted of a reactor with acetylcholinesterase (AChE) immobilized on a controlled pore glass and a detector with a tubular H+-selective membrane electrode. In order to examine the possibility of enhancing the sensitivity of the sensor by converting OPs to oxidized forms (stronger inhibitors), a comparison of the degree of enzyme inhibition by OPs at 10-6 M before and after their oxidation was made. All of the ten pesticides tested exhibited greater inhibitory power toward the sensor enzyme following oxidation. All of the oxidized pesticides at 10-6 M inhibited the sensor enzyme to a considerable degree, demonstrating the utility of the developed method for the class-specific determination of OPs. A calibration curve for diazinon, over the concentration range of 10-11-10-4 M, was obtained. The lower detection limit was 2 × 10-10 M. Treatment of the inhibited enzyme with pyridine-2-aldoxime restored the enzyme to near full activity, allowing repeated use of the sensor,