485799-04-0

Basic information

• Product Name: 6-(Morpholin-4-yl)pyridine-3-boronic acid pinacol ester
• Synonyms: 4-[5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-2-PYRIDINYL]MORPHOLINE;4-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDIN-2-YL]-MORPHOLINE;6-(MORPHOLIN-4-YL)PYRIDINE-3-BORONIC ACID PINACOL ESTER;6-MORPHOLINOPYRIDINE-3-BORONIC ACID, PINACOL ESTER;2-(4-MORPHOLINO)PYRIDINE-5-BORONIC ACID PINACOL ESTER;2-MORPHOLINOPYRIDINE-5-BORONIC ACID, PINACOL ESTER;2-(MORPHOLIN-4-YL)PYRIDINE-5-BORONIC ACID PINACOL ESTER;2-MORPHOLINE-4-YL-PYRIDINE-5-BORONIC ACID PINACOL ESTER
• CAS NO: 485799-04-0
• Molecular Formula: C₁₅H₂₃BN₂O₃
• Molecular Weight: 290.17
• Product Categories: Amino;Organoborons;Pyridine;Boric Acid| Boric Acid Ester| Potassium Trifluoroborate
• Mol File: 485799-04-0.mol

Chemical Properties

• Melting Point: 135-139 °C(lit.)
• Boiling Point: 440.929 °C at 760 mmHg
• Flash Point: 220.466 °C
• Appearance: /
• Density: 1.13 g/cm³
• Vapor Pressure: 5.67E-08mmHg at 25°C
• Refractive Index: 1.53
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 5.58±0.10(Predicted)
• CAS DataBase Reference: 6-(Morpholin-4-yl)pyridine-3-boronic acid pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(Morpholin-4-yl)pyridine-3-boronic acid pinacol ester(485799-04-0)
• EPA Substance Registry System: 6-(Morpholin-4-yl)pyridine-3-boronic acid pinacol ester(485799-04-0)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 22-24/25-45-43A-36/37/39-26
• RIDADR: 2811
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 485799-04-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
6-(Morpholin-4-yl)pyridine-3-boronic acid pinacol ester is used as a key building block for the synthesis of various pharmaceuticals. Its boronic acid functionality allows for the formation of carbon-carbon bonds, enabling the creation of diverse drug molecules with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 6-(Morpholin-4-yl)pyridine-3-boronic acid pinacol ester is employed as a vital component in the development of agrochemicals. Its ability to form carbon-carbon bonds through cross-coupling reactions contributes to the synthesis of novel agrochemicals with improved efficacy and selectivity.
Used as a Ligand in Metal-Catalyzed Reactions:
6-(Morpholin-4-yl)pyridine-3-boronic acid pinacol ester is utilized as a ligand in metal-catalyzed reactions. Its presence enhances the efficiency and selectivity of these reactions, leading to the production of desired products with fewer side reactions.
Used in the Synthesis of Biologically Active Molecules:
6-(Morpholin-4-yl)pyridine-3-boronic acid pinacol ester is employed as a key intermediate in the synthesis of biologically active molecules. Its unique structure and reactivity enable the creation of molecules with potential applications in various biological and medicinal fields.
Used in Organic Synthesis:
6-(Morpholin-4-yl)pyridine-3-boronic acid pinacol ester is used as a valuable tool in organic synthesis. Its pinacol ester derivative provides stability and protection against potential side reactions, making it an essential component in the synthesis of complex organic molecules.

InChI:InChI=1/C15H23BN2O3/c1-14(2)15(3,4)21-16(20-14)12-5-6-13(17-11-12)18-7-9-19-10-8-18/h5-6,11H,7-10H2,1-4H3

Upstream product

• 73183-34-3 bis(pinacol)diborane 
• 200064-11-5 5-bromo-2-(4-morpholinyl)pyridine 
• 53939-30-3 5-bromo-2-chloropyridine 

Downstream Products

• 1083428-82-3 6-(4-ethoxy-3-methoxy-phenyl)-2-methyl-3-(6-morpholin-4-yl-pyridin-3-yl)-imidazo[1,2-b]pyridazine 
• 1083428-86-7 6-(4'-methoxy-biphenyl-4-yl)-2-methyl-3-(6-morpholin-4-yl-pyridin-3-yl)-imidazo[1,2-b]pyridazine 
• 1040376-61-1 4-[1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-6-(6-morpholin-4-yl-pyridin-3-yl)-pyridazin-3-ylamine 
• 1258234-38-6 4-(5-(4-((2R,5R)-2,5-bis(4-chloro-3-nitrophenyl)pyrrolidin-1-yl)phenyl)pyridin-2-yl)morpholine 
• 1258234-64-8 4-(5-(3-((2R,5R)-2,5-bis(4-chloro-3-nitrophenyl)pyrrolidin-1-yl)phenyl)pyridin-2-yl)morpholine 
• 1374261-24-1 1-{4-[2(6-morpholin-4-ylpyridin-3-yl)-9H-imidazo[1,2-d]pyrido[2,3-b][1,4]benzodiazepin-3-yl]phenyl}cyclobutanamine 
• 1383990-11-1 2-amino-6-(6-morpholinopyridin-3-yl)-3-phenylquinazolin-4(3H)-one 
• 1431700-83-2 C₂₇H₂₉N₅O₄ 
• 1491155-61-3 3-(5-tert-butyl-2-hydroxyphenyl)-5-[6-(morpholin-4-yl)pyridin-3-yl]-3-phenyl-1,3-dihydro-2H-indol-2-one 
• 259260-15-6 1-(6-morpholinopyridin-3-yl)-3-phenylpropanone 

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