486-91-9 Usage
Indole family derivative
Yes
Hetero cyclic compound
Contains a pyridine ring fused to an indole ring
Tetrahydro derivative
Contains four hydrogen atoms added to its molecular structure
Methyl groups
Two attached to the first and second carbon atoms of the pyridine ring
Potential use
As an intermediate in the synthesis of pharmaceuticals
Biological activities
May possess activities that make it useful for research and development in the pharmaceutical industry
Check Digit Verification of cas no
The CAS Registry Mumber 486-91-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 6 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 486-91:
(5*4)+(4*8)+(3*6)+(2*9)+(1*1)=89
89 % 10 = 9
So 486-91-9 is a valid CAS Registry Number.
486-91-9Relevant articles and documents
A versatile linkage strategy for solid-phase synthesis of N,N-dimethyltryptamines and β-carbolines
Wu, Tom Y. H.,Schulte, Peter G.
, p. 4033 - 4035 (2002)
(matrix presented) Various tryptamines are captured by a vinylsulfonylmethyl polystyrene resin, generating a safety-catch linkage. β-Carbolines can be formed from 4 by a Pictet-Spengler reaction with the introduction of R1. Tryptamine 4 can also be derivatized by acylation or copper-mediated coupling to introduce R2. If X = Br, Suzuki coupling can be used to introduce R3. After derivatization, the indole derivatives are activated with methyl iodide and released under mild basic condition.
