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Usage

Uses

Used in Pharmaceutical Industry:
(R)-C3-TUNEPHOS is used as a ligand for asymmetric hydrogenation reactions, enabling the production of enantiomerically pure compounds. These compounds are vital in the development of single-enantiomer drugs, which have specific therapeutic effects and reduced side effects compared to their racemic counterparts.
Used in Chemical Industry:
(R)-C3-TUNEPHOS is used as a ligand for the asymmetric hydrogenation of ketones, facilitating the stereoselective preparation of arylalkyl esters. This application is crucial in the synthesis of various fine chemicals and pharmaceutical intermediates.
Used in Catalyst Development:
(R)-C3-TUNEPHOS is used as a precatalyst in enantioselective iridium-catalyzed carbonyl allylation reactions. This process involves the transfer hydrogenative coupling of allyl acetate from alcohol or aldehyde, allowing for the efficient synthesis of complex molecules with high enantioselectivity.
Used in Enantioselective Hydrogenation:
(R)-C3-TUNEPHOS is used as a catalyst in the enantioselective hydrogenation of α-keto esters to α-hydroxy esters using Ru-tunephos catalysts. This reaction is essential in the production of chiral alcohols, which are key building blocks in the synthesis of various pharmaceuticals and agrochemicals.