486439-05-8Relevant academic research and scientific papers
Structure-activity relationship of (1-Aryl-2-piperazinylethyl) piperazines: Antagonists for the AGRP/melanocortin receptor binding
Arasasingham, Premilla N.,Fotsch, Christopher,Ouyang, Xiaohu,Norman, Mark H.,Kelly, Michael G.,Stark, Kevin L.,Karbon, Bill,Hale, Clarence,Baumgartner, James W.,Zambrano, Martha,Cheetham, Janet,Tamayo, Nuria A.
, p. 9 - 11 (2007/10/03)
Agouti-related protein (AGRP) is an endogenous antagonist of the melanocortin action. In the hypothalamus, melanocortin peptide agonists act as satiety-inducing factors that mediate their action through the melanocortin-4 receptor (MC4R) whereas AGRP is a
Cyclic voltammetry as an indicator of antioxidant activity
Papanikos, Alexandra,Eklund, John,Jackson, W. Roy,Kenche, Vijaya B.,Campi, Eva M.,Robertson, Alan D.,Jarrott, Bevyn,Beart, Philip M.,Munro, Fiona E.,Callaway, Jennifer K.
, p. 205 - 212 (2007/10/03)
A series of compounds based around combining the neuroprotective properties of non-competitive N-methyl D-aspartic acid (NMDA) receptor antagonists with antioxidant functionalities have been prepared. The redox chemistry of these compounds has been evalua
