486443-96-3

Basic information

• Product Name: 5-bromo-3-(2,3-dimethoxybenzylidene)-1,3-dihydro-2H-indol-2-one
• Synonyms: 5-bromo-3-(2,3-dimethoxybenzylidene)-1,3-dihydro-2H-indol-2-one
• CAS NO: 486443-96-3
• Molecular Formula: C17H14BrNO3
• Molecular Weight: 360.20196
• Mol File: 486443-96-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-bromo-3-(2,3-dimethoxybenzylidene)-1,3-dihydro-2H-indol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-3-(2,3-dimethoxybenzylidene)-1,3-dihydro-2H-indol-2-one(486443-96-3)
• EPA Substance Registry System: 5-bromo-3-(2,3-dimethoxybenzylidene)-1,3-dihydro-2H-indol-2-one(486443-96-3)

Safety Data

• Hazardous Substances Data: 486443-96-3(Hazardous Substances Data)

Upstream product

• 124840-61-5 2-(5-bromo-2-nitrophenyl)aceticacid 
• 52414-98-9 5-bromo-2-nitrotoluene 
• 20870-78-4 5-bromo-2-indolin-2-one 
• 86-51-1 2,3-dimethyoxybenzaldehyde 

Relevant articles and documents

Synthesis and biological evaluation of 3-ethylidene-1,3-dihydro-indol-2- ones as novel checkpoint 1 inhibitors

Chk1 inhibitors have emerged as a novel class of neoplastic agents for abrogating the G2 DNA damage checkpoint arrest. Analogs of the Chk1 inhibitor, 3-ethylidene-1,3-dihydro-indol-2-one, were synthesized and tested in vitro for their inhibitory activitie