486445-06-1

Upstream product

• 811-98-3 d⁽⁴⁾-methanol 
• 830-79-5 2,4,6-trimethoxybenzaldehyde 
• 1076-59-1 3-phenyl-4H-isoxazol-5-one 

Relevant academic research and scientific papers

C,C- and C,N-linked dimers and 4-arylmethyl derivatives from 4-arylmethylene pyrazol-5-ones and isoxazol-5-ones with 2-arylbenzimidazolines

2-Arylbenzimidazolines (8), generated in situ from o-phenylenediamine (7) and the appropriate arylaldehydes, by reaction with 4-arylmethylene pyrazol-5-ones (1) or isoxazol-5-ones (2) produce the 4-arylmethyl derivatives (3) or (4) and the C,C- (5) or the C,N-linked dimers. The reaction was rationalised on the basis of the role of 2-arylbenzimidazoline as a reducing agent and proceeds by a non-chain, free radical process involving one-electron transfer.

Proton-catalysed E-Z isomerisation and Pd(II) assisted carbon-carbon cleavage on 3-phenyl-4-(2,4,6-trimethoxyphenyl)methyleneisoxazolin-5-one

Proton electrophilic addition to 3-phenyl-4-(2,4,6-trimethoxyphenyl)-methyleneisoxazolin-5-one can either catalyse E-Z isomerisation or a Pd(II) assisted cleavage of the exocyclic sp2-hybridised C-C bond in dependence on the proton site attack.