487000-87-3Relevant academic research and scientific papers
Synthesis of Enantiomerically Pure 2,2,3,4,5-Pentasubstituted Pyrrolidines by Phenylsulfanyl Migration
Baldwin, I. Craig,Briner, Paul,Eastgate, Martin D.,Fox, David J.,Warren, Stuart
, p. 4381 - 4384 (2007/10/03)
(Matrix Presented) Enantiomerically pure 2,2,3,4,5-pentasubstituted pyrrolidines can be prepared, in high overall yield, from α,β-unsaturated esters. Asymmetry is introduced via a Michael addition, and additional stereogenic centers are introduced by an a
