487004-87-5

Upstream product

• 696-59-3 cis,trans-2,5-dimethoxytetrahydrofuran 
• 115073-27-3 6-acetyl-5-amino-4-methyl-2-phenylthieno[2,3-d]pyrimidine 
• 2228-12-8 6-methyl-4-phenyl-2-thioxo-1,2-dihydropyrimidine-5-carbonitrile 

Downstream Products

• 877204-62-1 6-(2,2-dicyano-1-methylvinyl)-5-(1-pyrrolyl)-4-methyl-2-phenylthieno[2,3-d]pyrimidine 

Relevant academic research and scientific papers

Reactions of 6-acetyl-4-methyl-5-(1-pyrrolyl)-2-phenylthieno-[2,3-d] pyrimidine in heterocyclic synthesis: Convenient route to some Schiff's bases, chalcones, pyridines, pyridin-2(1H)-ones and 2H-pyran-2-one derivatives incorporating a 5-(1-pyrrolyl)-2-ph

Treatment of 6-acetyl-5-amino-4-methyl-2-phenylthieno[2,3-d]pyrimidine 3 with 2,5-dimethoxytetrahydrofuran afforded the 6-acetyl-5-(1-pyrrolyl)-4-methyl- 2-phenylthieno[2,3-d]pyrimidine 4, which can react with appropriate primary amines 5a-f to yield the

Synthesis of novel pyrrylthieno-[2,3-d]pyrimidines and related pyrrolo[1″,2″:1′,6′]pyrazino-[2′,3′:4,5] thieno[2,3-d]pyrimidines

4-Methyl-2-phenyl-5-(1-pyrryl)-6-substituted-thieno[2,3-d]pyrimidines (3a-c, 4a-c, 5a,b, and 6) have been synthesized. Some of the substituents in position 6 were used to build up different sulfur-, nitrogen-and/or oxygen-containing heterocyclic rings at that position. The 4-methyl- 2-phenyl-5-(1-pyrryl)-thieno[2,3-d]pyrimidine-6-carboazide (20) was also used as a key intermediate in the synthesis of the target pyrrolo[1″,2″:1′,6′]pyrazino[2′,3′:4, 5/thieno[2,3-d]pyrimidines.