487005-06-1Relevant academic research and scientific papers
Synthesis and structure of novel thieno[2,3-d]pyrimidine derivatives containing 1,3,4-oxadiazole moiety
Ho, Yuh-Wen,Suen, Maw-Cherng
experimental part, p. 408 - 415 (2009/12/06)
The reaction of 5-(1-pyrrolyl)-4-methyl-2-phenylthieno[2,3-d]pyrimidine carbohydrazide 5 with CS2 in the presence of pyridine afforded the 6-(2,3-dihydro-2-mercapto-1,3,4-oxadiazol-5-yl)-4-methyl-5-(1-pyrrolyl) -2-phenylthieno[2,3-d]pyrimidine
Synthesis of novel pyrrylthieno-[2,3-d]pyrimidines and related pyrrolo[1″,2″:1′,6′]pyrazino-[2′,3′:4,5] thieno[2,3-d]pyrimidines
Bakhite,Geies,El-Kashef
, p. 303 - 323 (2007/10/03)
4-Methyl-2-phenyl-5-(1-pyrryl)-6-substituted-thieno[2,3-d]pyrimidines (3a-c, 4a-c, 5a,b, and 6) have been synthesized. Some of the substituents in position 6 were used to build up different sulfur-, nitrogen-and/or oxygen-containing heterocyclic rings at that position. The 4-methyl- 2-phenyl-5-(1-pyrryl)-thieno[2,3-d]pyrimidine-6-carboazide (20) was also used as a key intermediate in the synthesis of the target pyrrolo[1″,2″:1′,6′]pyrazino[2′,3′:4, 5/thieno[2,3-d]pyrimidines.
