4874-36-6 Usage
Uses
Used in Vaccine Preservation:
5-Mercaptomethyluracil is used as a preservative in vaccines for preventing bacterial and fungal contamination. Its ability to act as a reducing agent helps maintain the stability and safety of the vaccine formulations.
Used in Medical Products:
Thiomersal is also used as a preservative in other medical products to ensure their sterility and prevent contamination, contributing to the overall safety and efficacy of these products.
Used in Topical Antiseptic Applications:
5-Mercaptomethyluracil is used as a topical antiseptic due to its antimicrobial properties, helping to prevent infections and promote healing in various skin conditions.
Used in Treatment of Skin Conditions:
Thiomersal has been used as a treatment for various skin conditions, leveraging its antimicrobial and anti-inflammatory properties to alleviate symptoms and promote skin health.
However, concerns have been raised about the potential toxicity of thiomersal, and its use in vaccines has become controversial. This has led to its removal from many vaccine formulations as a precautionary measure. The safety and efficacy of thiomersal continue to be a topic of ongoing research and debate in the scientific community.
Check Digit Verification of cas no
The CAS Registry Mumber 4874-36-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,8,7 and 4 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4874-36:
(6*4)+(5*8)+(4*7)+(3*4)+(2*3)+(1*6)=116
116 % 10 = 6
So 4874-36-6 is a valid CAS Registry Number.
InChI:InChI=1/C5H6N2O2S/c8-4-3(2-10)1-6-5(9)7-4/h1,10H,2H2,(H2,6,7,8,9)
4874-36-6Relevant academic research and scientific papers
Compounds inhibiting the aggregation of superoxide dismutase-1
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Page/Page column 22; sheet 14, (2008/06/13)
The invention is directed to methods of inhibiting the rate at which superoxide dismutse-1 (SOD) aggregates using compounds that stabilize SOD dimers. The methods are useful in the study and therapy of amyotrophic lateral sclerosis. The invention also includes assays that can be used to identify compounds that stabilize dimers and SOD molecules that have been modified for use in these assays.
Improved nucleic acid triggered probe activation through the use of a 5-thiomethyluracil peptide nucleic acid building block
Cai, Jianfeng,Li, Xiaoxu,Taylor, John Stephen
, p. 751 - 754 (2007/10/03)
(Chemical Equation Presented) To improve the efficiency of a nucleic acid triggered probe activation (NATPA) system a 5-thiomethyluracil peptide nucleic acid (PNA) building block has been synthesized. Attachment of imidazole and a coumarin ester to uracils at the ends of two PNAs resulted in a 550 000-fold acceleration of DNA-triggered coumarin release relative to imidazole and a 6-fold increase in kcat relative to a system which had these groups attached to the amino and carboxy ends of PNAs.
