488124-29-4

Upstream product

• 590-37-4 2-methylpent-4-yn-2-ol 
• 488124-20-5 (3aS,5aR,6S,9aR)-3a,4,5,5a,6,7,8,9-octahydro-6-hydroxycyclopenta[c]inden-3(3H)-one 
• 488124-22-7 (1S,4S,7R,8S,12S)-3-methyl-2,13-dioxatetracyclo[6.5.0.0^4,8.0^7,12]tridecan-3-ol 
• 488124-24-9 (3aS,5aR,6S,9aR)-6-{[(tert-butyl)(dimethyl)silyl]oxy}-3a,4,5,5a,6,7,8,9-octahydrocyclopenta[c]inden-3(3H)-one 
• 488124-25-0 (3aS,5aR,6S,9aR)-6-{[(tert-butyl)(dimethyl)silyl]oxy}decahydrocyclopenta[c]inden-3(3H)-one 
• 488124-26-1 (3aS,5aR,6S,9aR)-6-{[(tert-butyl)(dimethyl)silyl]oxy}-3a,4,5,5a,6,7,8,9-octahydro-1H-cyclopenta[c]inden-3-yl trifluoromethanesulfonate 

Relevant academic research and scientific papers

Synthesis of tetracyclic analogues of calcitriol (1α,25-dihydroxyvitamin D3) with side-chain-locked spatial orientations at C(20)

We present our first results on the synthesis of a new class of conformationally restricted vitamin D analogues bearing an extra five-membered ring formed by linking C(18) and C(21). Two analogues of calcitriol (1) with unsaturations at the extra ring and