488128-98-9

Basic information

• Product Name: 1,4-Naphthalenedione, 2-chloro-3-[(2,4-dinitrophenyl)amino]-
• CAS NO: 488128-98-9
• Molecular Formula: C16H8ClN3O6
• Molecular Weight: 373.709
• Mol File: 488128-98-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1,4-Naphthalenedione, 2-chloro-3-[(2,4-dinitrophenyl)amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Naphthalenedione, 2-chloro-3-[(2,4-dinitrophenyl)amino]-(488128-98-9)
• EPA Substance Registry System: 1,4-Naphthalenedione, 2-chloro-3-[(2,4-dinitrophenyl)amino]-(488128-98-9)

Safety Data

• Hazardous Substances Data: 488128-98-9(Hazardous Substances Data)

Upstream product

• 1090-16-0 2-chloro-3-(phenylamino)naphthalene-1,4-dione 
• 117-80-6 2,3-Dichloro-1,4-naphthoquinone 
• 97-02-9 2,4-Dinitroanilin 
• 62-53-3 aniline 

Relevant articles and documents

Palladium-catalyzed amination of 2,3-dichloro-1,4-naphthoquinone with nitroarylamines

A convenient one-step synthesis of 2-[(nitroaryl)amino]-3-chloro-1,4- naphthoquinones is reported. The direct amination of 2,3-dichloro-1,4- naphthoquinone with nitro-substituted aryl amines is catalyzed by PdCl 2(dppf)/dppf in the presence of

Synthesis and studies of the antifungal activity of 2-anilino-/2,3-dianilino-/2-phenoxy- and 2,3-diphenoxy-1,4-naphthoquinones

Several synthetic and natural naphthoquinone derivatives have been associated with antifungal activity. Candida albicans is a fungus that is known to exist in the normal human flora, but under certain conditions it can cause mild to fatal infections. Its pathogenicity has been associated with fungus conversion from cellular yeast to filamentous form Y–M. Inhibition of this process by several anilino-, dianilino-, phenoxy-, and diphenoxy-1,4-naphthoquinones was investigated in order to find some correlation between structure, redox properties and biological activity.

Direct nitration of 3-arylamino-2-chloro-1,4-naphthoquinones

A convenient two-step synthesis of mononitro and dinitro derivatives of the title compounds is reported. The Michael type addition of aromatic amines to 2,3-dichloro-1,4-naphthoquinone, is followed by mixed acids nitration to yield nitro aromatic quinones