488150-29-4Relevant academic research and scientific papers
A comparison of phosphonium and phosphonate carbanion reagents in reactions with 1,3-diphenyl-2-(hydroxyimino)-1,3-propanedione
Abdou, Wafaa M.,El-Khoshnieh, Yehia O.,Salem, Mounir A. I.,Barghash, Reham F.
, p. 1417 - 1422 (2007/10/03)
1,3-Diphenyl-2-(hydroxyimino)-1,3-propanedione 1 reacted with phosphonium ylides 2a,b to give mainly the substituted 1-hydroxy-2,3-dihydropyrroles 6a,b along with the novel ylides 10a,b whereas the phosphono substituted-N-heterocycles 11a,b and 14a,b were obtained from the reaction of 1 with α-phosphoryl carbanion counterparts 3a,b. Reaction of 1 with cyanomethylene(triphenyl)phosphorane 2c afforded the Wittig product 17 and the oxazole derivative 18 while the phosphono 2,2-disubstituted dihydrooxazole 20 and the diolefin 19 were produced in the reaction with the phosphonate ylide 3c. Application of the unsaturated carbanions 2d and 3d on 1 yielded the pyrrole 23 and the phosphono substituted 2H-1,4-oxazine 25, respectively.
