488151-89-9Relevant academic research and scientific papers
Substituent effects on the amination of racemic allyl carbonates using commercially available chiral rhodium catalysts
Atallah, Timothy,Blankespoor, Ronald L.,Homan, Philip,Hulderman, Chase,Samas, Brian M.,Van Allsburg, Kurt,Vrieze, Derek C.
, p. 5795 - 5798 (2013/10/01)
In the presence of commercially available chiral rhodium catalysts, a competitive benzy lamination of racemic allyl carbonates, substituted with p-X-Ph groups, shows that the reaction proceeds faster with substituents (X) that are more electron-withdrawing. Mechanistic implications of these results are discussed.
ENANTIOSELECTIVE AMINATION AND ETHERIFICATION___________________
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Page 17-19; 42-43, (2010/02/06)
The present invention is directed to a catalyst composition, comprising: (1) a catalyst precursor having the general structure MSXn wherein M is a transition metal selected from the group consisting of iridium, molybdenum, and tungsten; S is a coordinating ligand; X is a counterion; and n is an integer from 0 to 5; and (2) a phosphoramidite ligand having the structure wherein O-Cn-O is an aliphatic or aromatic diolate and wherein R1, R2, R3 and R4 are selected from the group consisting of substituted or unsubstituted aryl groups, substituted or unsubstituted heteroaryl groups, substituted or unsubstituted aliphatic groups, and combinations thereof, with the proviso that at least one of R1, R2, R3, or R4 must be a substituted or unsubstituted aryl or heteroaryl group. The present invention is also directed to activated catalysts made from the above catalyst composition, as well as methods of allylic amination and etherification using the above catalysts.
