488743-75-5

Upstream product

• 35718-08-2 propargyl chloroformate 
• 3162-96-7 4,6-O-benzylidene-1-O-methyl-α-D-glucopyranoside 
• 97-30-3 methyl-alpha-D-glucopyranoside 
• 1125-88-8 benzaldehyde dimethyl acetal 

Downstream Products

• 488744-09-8 Carbonic acid (2R,4aR,6S,7R,8S,8aR)-6-methoxy-2-phenyl-8-((2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yloxy)-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl ester prop-2-ynyl ester 
• 488743-93-7 Carbonic acid (2R,4aR,6S,7R,8S,8aR)-8-allyloxycarbonyloxy-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl ester prop-2-ynyl ester 
• 488744-04-3 Acetic acid (2S,3R,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-2-((2R,4aR,6S,7R,8S,8aR)-6-methoxy-2-phenyl-7-prop-2-ynyloxycarbonyloxy-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-tetrahydro-pyran-3-yl ester 
• 488743-90-4 Carbonic acid (2R,4aR,6S,7R,8S,8aR)-8-benzyloxycarbonyloxy-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl ester prop-2-ynyl ester 
• 488743-91-5 methyl 4,6-O-benzylidene-3-O-Cbz-α-D-glucopyranoside 
• 2872-56-2 methyl 3-O-acetyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 488743-97-1 4-Oxo-pentanoic acid (2R,4aR,6S,7R,8S,8aR)-6-methoxy-2-phenyl-7-prop-2-ynyloxycarbonyloxy-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester 
• 488743-95-9 Acetic acid (2R,4aR,6S,7R,8S,8aR)-6-methoxy-2-phenyl-7-prop-2-ynyloxycarbonyloxy-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester 

Relevant academic research and scientific papers

Propargyloxycarbonyl (Poc) as a Protective Group for the Hydroxyl Function in Carbohydrate Synthesis

(Matrix Presented) The propargyloxycarbonyl (Poc) group can be used for the selective protection of the hydroxyl function in carbohydrates and can be removed under neutral conditions using tetrathiomolybdate MoS42- (1) in CH3CN at room temperature. Under the conditions of deprotection benzylidine acetals, benzyl ethers, acetyl and levulinoyl esters, and allyl and benzyl carbonates are left untouched. It has also been shown that the new protective group (Poc) is compatible with acidic, basic, and also glycosylation conditions.