488794-92-9

Upstream product

• 488794-82-7 8-(R)-3'-N-demethyl-8a-oxa-2'-O,3'-N,4''-O-tris(benzyloxycarbonyl)-8a-homoerythromycin A cyclic 11,12-carbonate 
• 501-53-1 benzyl chloroformate 
• 488794-78-1 3'-N-demethyl-6-deoxy-6,9-epoxy-7,8-nor-6-(2-oxopropyl)-2'-O,3'-N,4''-O-tris(benzyloxycarbonyl)erythromycin A cyclic 11,12-carbonate 
• 488794-99-6 3'-N-demethyl-6-deoxy-6,9-epoxy-6-[(S)-2-hydroxypropyl]-7,8-nor-2'-O,3'-N,4''-O-tris(benzyloxycarbonyl)erythromycin A cyclic 11,12-carbonate 
• 488794-80-5 3'-N-demethyl-6-deoxy-6,9-epoxy-6-[(R)-2-hydroxypropyl]-7,8-nor-2'-O,3'-N,4''-O-tris(benzyloxycarbonyl)erythromycin A cyclic 11,12-carbonate 

Relevant academic research and scientific papers

Novel antibacterial macrolides: Synthesis of 15-membered diolides

Novel 15-membered macrolides possessing the dilactone skeleton, diolides 13a and 13b, have been synthesized in our research program aimed at finding new antibacterial macrolides. Key strategic elements of the approach include the ring-expanding reaction o