488835-81-0

Basic information

• Product Name: methyl (2R,3R)-3-(4-benzyloxyphenyl)-2-tert-butoxycarbonylamino-3-methoxypropionic acid
• Synonyms: methyl (2R,3R)-3-(4-benzyloxyphenyl)-2-tert-butoxycarbonylamino-3-methoxypropionic acid
• CAS NO: 488835-81-0
• Molecular Weight: 401.459
• Mol File: 488835-81-0.mol

Chemical Properties

• CAS DataBase Reference: methyl (2R,3R)-3-(4-benzyloxyphenyl)-2-tert-butoxycarbonylamino-3-methoxypropionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (2R,3R)-3-(4-benzyloxyphenyl)-2-tert-butoxycarbonylamino-3-methoxypropionic acid(488835-81-0)
• EPA Substance Registry System: methyl (2R,3R)-3-(4-benzyloxyphenyl)-2-tert-butoxycarbonylamino-3-methoxypropionic acid(488835-81-0)

Safety Data

• Hazardous Substances Data: 488835-81-0(Hazardous Substances Data)

Upstream product

• 488835-82-1 (4S)-4-[(1R)-1-(4-benzyloxyphenyl)hydroxymethyl]-3-tert-butoxycarbonyl-2,2-dimethyloxazolidine 
• 488835-86-5 (4S)-4-[(1R)-1-(4-benzyloxyphenyl)methoxymethyl]-3-tert-butoxycarbonyl-2,2-dimethyloxazolidine 
• 488835-85-4 (4S)-4-(4-benzyloxyphenyl)-3-tert-butoxycarbonyl-2,2-dimethyloxazolidine 
• 488835-87-6 (2S,3R)-3-(4-benzyloxyphenyl)-2-tert-butoxycarbonylamino-3-methoxy-1-propanol 
• 102308-32-7 (4S)-4-formyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 6793-92-6 p-benzyloxyphenylbromide 

Downstream Products

• 868151-82-0 (S)-1-[(2R,3R)-2-[(2S,3R)-2-(Benzyloxycarbonyl-methyl-amino)-3-(tert-butyl-dimethyl-silanyloxy)-butyrylamino]-3-(4-benzyloxy-phenyl)-3-methoxy-propionyl]-piperidine-2-carboxylic acid benzyl ester 
• 868151-86-4 (S)-1-[(2R,3R)-2-[(2S,3R)-2-(Benzyloxycarbonyl-methyl-amino)-3-hydroxy-butyrylamino]-3-(4-benzyloxy-phenyl)-3-methoxy-propionyl]-piperidine-2-carboxylic acid benzyl ester 
• 868151-78-4 (S)-1-[(2R,3R)-3-(4-Benzyloxy-phenyl)-2-tert-butoxycarbonylamino-3-methoxy-propionyl]-piperidine-2-carboxylic acid benzyl ester 

Relevant articles and documents

Dynamic kinetic resolution catalyzed by Ir axially chiral phosphine catalyst: Asymmetric synthesis of anti aromatic β-hydroxy-α-amino acid esters

The anti selective hydrogenation of α-amino-β-keto esters via dynamic kinetic resolution was achieved for the first time by using the iridium-MeOBIPHEP catalyst in asymmetric synthesis of anti aromatic β-hydroxy-α-amino acid esters with excellent diastereo- and enantioslectivities. Acetic acid as a solvent and sodium acetate as an additive affected dramatically the yield and the enantioselectivity, respectively. The product anti aromatic β-hydroxy-α-amino acid esters are useful for synthesis of pharmaceuticals and natural products. Copyright

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