488843-85-2

Upstream product

• 126922-09-6 ethyl 2-(4-cyano-1-phenyl-6,7-dihydro-5H-cyclopenta[c]pyridin-3-yloxy)acetate 
• 487024-75-9 C₁₅H₁₁ClN₂ 
• 126921-96-8 3-oxo-1-phenyl-3,5,6,7-tetrahydro-2H-cyclopenta[c]pyridine-4-carbonitrile 

Relevant academic research and scientific papers

New Methods for the Synthesis of 3-Amino-6,7-Dihydro-5H-Cyclopenta[c]Pyridine-4-Carbonitriles and Cyclopenta[d]Pyrazolo[3,4-b]Pyridines via a Smiles-type Rearrangement

By reaction with sodium ethoxide and as a function of their structures, 2-[(1-alkyl(aryl)-4-cyano-6,7-dihydro-5H-cyclopenta[c]pyridin-3-yl)oxy]acetamides 11 gave 1-amino-5-alkyl(aryl)-7,8-dihydro-6H-cyclopenta[d]furo[2,3-b]pyridine-2-carboxamides 10 and/or 1-alkyl(aryl)-3-amino-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitriles 12.

EPHA4 RTK INHIBITORS FOR TREATMENT OF NEUROLOGICAL AND NEURODEGENERATIVE DISORDERS AND CANCER

The present invention is directed to compounds of generic formula (I) which are inhibitors of ephrin A4. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatm