488846-84-0Relevant articles and documents
N-(3-amino-2-hydroxy-propyl) substd. alkylamidoalkanol compd.
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Page/Page column 135, (2008/06/13)
Disclosed are compounds of the formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.