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3-(3-chlorophenyl)-3H-isobenzofuran-1-one is a chemical compound with the molecular formula C13H7ClO2. It is a derivative of isobenzofuran, featuring a 3-chlorophenyl group attached to the 3-position of the isobenzofuran ring. 3-(3-chlorophenyl)-3H-isobenzofuran-1-one is characterized by its aromatic structure, with the isobenzofuran ring system providing a fused ring arrangement that includes a benzene ring and a furan ring. The presence of the chlorine atom on the phenyl group introduces a halogenated feature, which can significantly alter the compound's reactivity and physical properties compared to non-halogenated analogs. This chemical is primarily of interest in organic chemistry and may have potential applications in the synthesis of pharmaceuticals or other specialty chemicals due to its unique structural features.

4889-71-8

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4889-71-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4889-71-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,8,8 and 9 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 4889-71:
(6*4)+(5*8)+(4*8)+(3*9)+(2*7)+(1*1)=138
138 % 10 = 8
So 4889-71-8 is a valid CAS Registry Number.

4889-71-8Downstream Products

4889-71-8Relevant academic research and scientific papers

Direct and selective synthesis of 3-arylphthalides via nickel-catalyzed aryl addition/intramolecular esterification

Qiang, Qing,Liu, Feipeng,Rong, Zi-Qiang

supporting information, (2021/05/10)

Herein we report a nickel-catalyzed aryl addition/intramolecular esterification in a cascade fashion. Under the combination of commercially available nickel precursor and tridentate ligand, the one pot protocol offers a direct, simple and regioselective approach to access 3-aryl phthalide derivatives from two readily available substrates with good efficiency, broad scope as well as satisfactory functional group compatibility.

Synthesis of biarylketones and phthalides from organoboronic acids and aldehydes catalyzed by cobalt complexes

Karthikeyan, Jaganathan,Parthasarathy, Kanniyappan,Cheng, Chien-Hong

supporting information; experimental part, p. 10461 - 10463 (2011/11/06)

A cobalt-catalyzed addition of aryl- and alkenylboronic acids to aldehydes and phthalaldehyde to give the corresponding biarylketones and 3-aryl phthalides in good to excellent yields in one pot is described.

Efficient synthesis of 3-arylphthalides using palladium-catalyzed arylation of aldehydes with organoboronic acids

Kuriyama, Masami,Ishiyama, Natsuki,Shimazawa, Rumiko,Shirai, Ryuichi,Onomura, Osamu

supporting information; experimental part, p. 9210 - 9213 (2010/03/03)

(Chemical Equation Presented) The synthesis of 3-arylphthalides via palladium-catalyzed arylation of aldehydes with organoboronic acids was achieved using the thioether-imidazolinium carbene ligand in good to excellent yields and was carried out using 1.0

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