489-18-9

Basic information

• Product Name: 1-(tert-butyl)-2-fluoro-4-nitrobenzene
• Synonyms: 1-(tert-butyl)-2-fluoro-4-nitrobenzene
• CAS NO: 489-18-9
• Molecular Weight: 197.209
• Mol File: 489-18-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1-(tert-butyl)-2-fluoro-4-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(tert-butyl)-2-fluoro-4-nitrobenzene(489-18-9)
• EPA Substance Registry System: 1-(tert-butyl)-2-fluoro-4-nitrobenzene(489-18-9)

Safety Data

• Hazardous Substances Data: 489-18-9(Hazardous Substances Data)

Usage

Structure

A derivative of benzene with a tert-butyl group at the 1 position, a fluorine atom at the 2 position, and a nitro group at the 4 position.

Applications

a. Organic synthesis
b. Building block in the production of pharmaceuticals and agrochemicals
c. Intermediate in the manufacture of dyes, pigments, and specialty chemicals

Physical state

Pale yellow solid at room temperature

Odor

Slightly fruity

Safety precautions

a. May be harmful if ingested
b. May be harmful if inhaled
c. May be harmful if it comes into contact with the skin

Upstream product

• 6310-21-0 2-(1,1-dimethylethyl)-benzenamine 
• 103392-84-3 2-tert-Butyl-5-nitro-phenylamine 

Downstream Products

• 850040-16-3 1-t-butyl-2-fluoro-4-nitrobenzene 

Relevant articles and documents

AZA-ARYL 1H-PYRAZOL-1-YL BENZENE SULFONAMIDES

Compounds are provided that act as potent antagonists of the CCR(9) receptor for treating Sjogren's syndrome. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions.

Heterocyclic compound

The present invention relates to compound (I) or a salt thereof which has a ROR γ t inhibitory action. wherein each symbol is as defined in the specification.

AZA-ARYL 1H-PYRAZOL-1-YL BENZENE SULFONAMIDES

Compounds are provided that act as potent antagonists of the CCR(9) receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR(9). The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR(9)-mediated diseases, and as controls in assays for the identification of CCR(9) antagonists.