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ML213 is a selective KV7.2 (KCNQ2) and KV7.4 (KCNQ4) channel opener, characterized by its high selectivity and potency with EC50 values of 230 and 510 nM for KV7.2 and KV7.4, respectively. It demonstrates over 80-fold selectivity against KV7.1, KV7.3, and KV7.5 in a thallium-based fluorescence assay.

489402-47-3

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489402-47-3 Usage

Uses

Used in Pharmaceutical Industry:
ML213 is used as a selective KV7.2 and KV7.4 channel opener for its potential therapeutic applications in various conditions, such as epilepsy, migraine, and atrial fibrillation. Its high selectivity and potency make it a promising candidate for the development of targeted treatments with minimal side effects.
Used in Research and Development:
ML213 is used as a research tool for studying the function and role of KV7.2 and KV7.4 channels in cellular processes and disease mechanisms. Its selectivity and potency allow researchers to investigate the specific contributions of these channels in various physiological and pathological conditions, leading to a better understanding of their roles and potential therapeutic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 489402-47-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,8,9,4,0 and 2 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 489402-47:
(8*4)+(7*8)+(6*9)+(5*4)+(4*0)+(3*2)+(2*4)+(1*7)=183
183 % 10 = 3
So 489402-47-3 is a valid CAS Registry Number.

489402-47-3 Well-known Company Product Price

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  • (Code)Product description
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  • Sigma

  • (SML0611)  ML213  ≥98% (HPLC)

  • 489402-47-3

  • SML0611-5MG

  • 761.67CNY

  • Detail

  • Sigma

  • (SML0611)  ML213  ≥98% (HPLC)

  • 489402-47-3

  • SML0611-25MG

  • 3,087.63CNY

  • Detail

489402-47-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-3-carboxamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:489402-47-3 SDS

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