SBC-115,076 is an anti-proprotein convertase subtilisin kexin type 9 (anti-PCSK9) compound, which is a novel therapeutic agent designed to target and modulate the activity of PCSK9. This protein plays a crucial role in the regulation of cholesterol levels in the body. By inhibiting PCSK9, SBC-115,076 can potentially lower low-density lipoprotein (LDL) cholesterol levels, making it a promising candidate for the treatment and prevention of cardiovascular diseases and hypercholesterolemia.
489415-96-5
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Basic information
- Product Name: sbc-115076
- Synonyms: sbc-115076;4-[hydroxy-(3-methyl-4-phenylmethoxyphenyl)methylidene]-1-(3-morpholin-4-ylpropyl)-5-pyridin-4-ylpyrrolidine-2,3-dione;1,5-Dihydro-3-hydroxy-4-[3-methyl-4-(phenylmethoxy)benzoyl]-1-[3-(4-morpholinyl)propyl]-5-(4-pyridinyl)-2H-pyrrol-2-one
- CAS NO:489415-96-5
- Molecular Formula: C31H33N3O5
- Molecular Weight: 527.61082
- EINECS: -0
- Product Categories: Inhibitors
- Mol File: 489415-96-5.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 754.2±60.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.266±0.06 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: Sealed in dry,Store in freezer, under -20°C
- Solubility: N/A
- PKA: 4.50±1.00(Predicted)
- CAS DataBase Reference: sbc-115076(CAS DataBase Reference)
- NIST Chemistry Reference: sbc-115076(489415-96-5)
- EPA Substance Registry System: sbc-115076(489415-96-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 489415-96-5(Hazardous Substances Data)
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489415-96-5 Usage
Uses
Used in Pharmaceutical Industry:SBC-115,076 is used as a therapeutic agent for the treatment and prevention of cardiovascular diseases and hypercholesterolemia. By targeting and inhibiting PCSK9, it helps to lower LDL cholesterol levels, reducing the risk of atherosclerosis and related complications.
Used in Research and Development:
SBC-115,076 is also utilized in research and development for the study of PCSK9's role in cholesterol regulation and the development of novel treatments for dyslipidemia and related conditions. Its application in research can contribute to a better understanding of the underlying mechanisms of cholesterol metabolism and the potential for targeted therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 489415-96-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,8,9,4,1 and 5 respectively; the second part has 2 digits, 9 and 6 respectively.Calculate Digit Verification of CAS Registry Number 489415-96:
(8*4)+(7*8)+(6*9)+(5*4)+(4*1)+(3*5)+(2*9)+(1*6)=205
205 % 10 = 5
So 489415-96-5 is a valid CAS Registry Number.
489415-96-5Upstream product
489415-96-5Downstream Products
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