489435-05-4 Usage
Uses
Used in Pharmaceutical Industry:
3-(4-bromophenyl)-5-(4-chlorophenyl)-1,2,4-oxadiazole is used as a key intermediate in the synthesis of pharmaceutical compounds for its potential therapeutic applications. Its unique structure allows for the development of new drugs with improved efficacy and selectivity.
Used in Materials Science:
In the field of materials science, 3-(4-bromophenyl)-5-(4-chlorophenyl)-1,2,4-oxadiazole is utilized as a component in the design and synthesis of advanced materials with specific properties. Its incorporation into materials can lead to enhanced performance in various applications, such as sensors, catalysts, or optoelectronic devices.
Used in Chemical Synthesis:
3-(4-bromophenyl)-5-(4-chlorophenyl)-1,2,4-oxadiazole is employed as a versatile building block in chemical synthesis, taking advantage of its bromo and chloro substituents for further functionalization and the formation of new compounds. This allows for the exploration of novel synthetic pathways and the development of innovative chemical entities.
Further research and exploration of the chemical and biological properties of 3-(4-bromophenyl)-5-(4-chlorophenyl)-1,2,4-oxadiazole may lead to the discovery of new applications and potential benefits across different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 489435-05-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,8,9,4,3 and 5 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 489435-05:
(8*4)+(7*8)+(6*9)+(5*4)+(4*3)+(3*5)+(2*0)+(1*5)=194
194 % 10 = 4
So 489435-05-4 is a valid CAS Registry Number.
489435-05-4Relevant academic research and scientific papers
CYCLIZATION AND ACID-CATALYZED HYDROLYSIS OF O-BENZOYLBENZAMIDOXIMES
Grambal, Frantisek,Lasovsky, Jan
, p. 2786 - 2797 (2007/10/02)
Kinetics of formation of 1,2,4-oxadiazoles from 24 substitution derivatives of O-benzoylbenzamidoxime have been studied in sulphuric acid and aqueous ethanol media.It has been found that this medium requires introduction of the Hammett H0 function instead of the pH scale beginning as low as from 0.1percent solutions of mineral acids.Effects of the acid concentration, ionic strength, and temperature on the reaction rate and on the kinetic isotope effect have been followed.From these dependences and from polar effects of substituents it was concluded that along with the cyclization to 1,2,4-oxadiazoles there proceeds hydrolysis to benzamidoxime and benzoic acid.The reaction is thermodynamically controlled by the acid-base equilibrium of the O-benzylated benzamidoximes.
