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1,2-Pyrrolidinedicarboxylic acid, 4-[[[(2R,4S)-4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-[(phenylmethoxy) carbonyl]-2-pyrrolidinyl]carbonyl]amino]-, 2-methyl 1-(phenylmethyl) ester, (2R,4S)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

489446-89-1

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489446-89-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 489446-89-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,8,9,4,4 and 6 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 489446-89:
(8*4)+(7*8)+(6*9)+(5*4)+(4*4)+(3*6)+(2*8)+(1*9)=221
221 % 10 = 1
So 489446-89-1 is a valid CAS Registry Number.

489446-89-1Relevant academic research and scientific papers

Synthesis and DNA binding properties of saturated distamycin analogues

Woods, Craig R.,Faucher, Nicolas,Eschgfaller, Bernd,Bair, Kenneth W.,Boger, Dale L.

, p. 2647 - 2650 (2007/10/03)

A series of saturated heterocyclic analogues of distamycin were prepared and examined. A fluorescent intercalator displacement (FID) assay conducted on p[dA]-p[dT] DNA to obtain C50 values and a hairpin deoxyoligonucleotide containing an A/T-rich binding site was used to evaluate DNA binding affinity. It is observed that saturated heterocycles greatly reduce the DNA binding relative to distamycin.

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