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3,4-dihydro-2,5,8-trimethyl-2-(4,8,12-trimethyl-trideca-3,7,11-trienyl)-2H-1-benzopyran-6-ol, also known as β-Tocotrienol, is a tocotrienol isomer of Vitamin E. It is characterized by a chroman-6-ol structure substituted by methyl groups at positions 2, 5, and 8, and a farnesyl chain at position 2. 3,4-dihydro-2,5,8-trimethyl-2-(4,8,12-trimethyl-trideca-3,7,11-trienyl)-2H-1-benzopyran-6-ol has been isolated from various sources, including wheat germ oil and bran.

490-23-3

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490-23-3 Usage

Uses

Used in Pharmaceutical Applications:
3,4-dihydro-2,5,8-trimethyl-2-(4,8,12-trimethyl-trideca-3,7,11-trienyl)-2H-1-benzopyran-6-ol is used as a pharmaceutical agent for its potential health benefits. As a form of Vitamin E, it possesses antioxidant properties that can help protect cells from damage caused by free radicals. Its antioxidant activity may contribute to its potential use in the prevention and treatment of various diseases, including cardiovascular diseases and certain types of cancer.
Used in Nutritional Supplements:
In the nutritional supplement industry, 3,4-dihydro-2,5,8-trimethyl-2-(4,8,12-trimethyl-trideca-3,7,11-trienyl)-2H-1-benzopyran-6-ol is used as an ingredient in dietary supplements for its antioxidant and potential health-promoting properties. It can be found in products that aim to support overall health and well-being, particularly in relation to maintaining a healthy immune system and promoting healthy aging.
Used in Cosmetics:
3,4-dihydro-2,5,8-trimethyl-2-(4,8,12-trimethyl-trideca-3,7,11-trienyl)-2H-1-benzopyran-6-ol is also used in the cosmetics industry for its antioxidant properties. It can be incorporated into skincare products to help protect the skin from environmental stressors, such as pollution and UV radiation, and may contribute to anti-aging effects by reducing the visible signs of aging, such as fine lines and wrinkles.

Check Digit Verification of cas no

The CAS Registry Mumber 490-23-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,9 and 0 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 490-23:
(5*4)+(4*9)+(3*0)+(2*2)+(1*3)=63
63 % 10 = 3
So 490-23-3 is a valid CAS Registry Number.
InChI:InChI=1/C28H42O2/c1-20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-24(6)26(29)19-23(5)27(25)30-28/h11,13,15,19,29H,8-10,12,14,16-18H2,1-7H3/b21-13+,22-15+/t28-/m1/s1

490-23-3 Well-known Company Product Price

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  • Sigma-Aldrich

  • (05644)  β-Tocotrienol  analytical standard

  • 490-23-3

  • 05644-100MG

  • 37,989.90CNY

  • Detail

490-23-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name β-tocotrienol

1.2 Other means of identification

Product number -
Other names beta-tocotrienol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:490-23-3 SDS

490-23-3Downstream Products

490-23-3Relevant academic research and scientific papers

SYNTHESIS OF TOCOTRIENOLS FROM O-CRESOL DERIVATIVES

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, (2019/04/11)

The present invention provides an environmentally benign, facile process for preparation of Tocotrienols from commercially available derivatives of o-Cresol.

A short and convenient chemical route to optically pure 2-methyl chromanmethanols. Total asymmetric synthesis of β-, γ-, and δ-tocotrienols

Couladouros, Elias A.,Moutsos, Vassilios I.,Lampropoulou, Maria,Little, James L.,Hyatt, John A.

, p. 6735 - 6741 (2008/02/11)

(Chemical Equation Presented) With use of inexpensive commercially available raw materials, chromanmethanol precursors to the natural β-, γ-, and δ-tocotrienols have been prepared in high yield. Enzymatic resolution afforded chiral chromanmethanols in high enantiomeric excess. Subsequent attachment of the farnesyl side chain was high yielding, thus allowing the preparation of asymmetric β-, γ-, and δ-tocotrienols in one final step wherein simultaneous deprotection of the phenol and removal of the sulfone group occurs. This chemistry provides the first synthesis of natural-series β-tocotrienol.

PROCESS FOR SYNTHESIZING d-TOCOTRIENOLS

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Page/Page column 21, (2010/02/11)

A process of forming a d-tocotrienols from a (2S) 2-hydroxymethyl-6--hydroxy-alkylchroman compound, through reaction with a farnesy1 Grignard or sulfone compound. Various methods of making the (2S) 2-hydroxymethyl-6-hydroxy- alklychroman compound are disclosed.

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