4901-93-3

Upstream product

• 13801-51-9 4-hydroxy-1,5-naphthyridine-3-carboxylic acid ethyl ester 
• 14029-71-1 2-(pyridin-3-yl)aminomethylene-malonic acid diethyl ester 
• 462-08-8 pyridin-3-ylamine 

Downstream Products

• 53512-20-2 (4-oxo-3,4-dihydro-[1,5]naphthyridine-3-carbonyloxy)-succinimide 
• 5423-54-1 4-hydroxy-1,5-naphthyridine 

Relevant academic research and scientific papers

Platinum complexes of 4-hydoxy-1,5-naphthyridines as emitting dyes

4-Hydoxy-1,5-naphthyridines (HNt) are derivatives of 8-hydroxyquinolines, yet possess a wider HOMO and LUMO band gap than the latter. The cyclometalated complex of platinum(II) with Nt exists in a square planner geometry, and has a high tendency to aggregate in condensedmedia. Such a phenomenon was verified by examining its photo-luminescence spectra in different concentrations. In a dilute solution, it exhibits a yellow phosphorescence centered at 530∑555 nm, yet red-shifted to ∑660 nm in a concentrated solution or in the solid state. This series of compounds can be used as emitting dyes in light-emitting diodes (LED). The LED devices with a configuration ITO/NPB/dye (6%) in CBP/BCP/AlQ3 or TPBI/LiF/Al displayed a yellow to red color, where NPB, CBP, BCP, AlQ3 and TPBI denote 4,4′-bis[N-(1-naphthyl), Nphenylamino] biphenyl, 4,4′-bis(carbazol-9-yl)biphenyl, 2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline, tris(8-hydoxyquinolinato) aluminium, and 2,2′,2′-(1,3,5-benzenetriyl)tris(1-phenyl-1H- benzimidazole), respectively. The maximal light intensity exceeds 2.6 × 104 cd/m2 with an external quantum efficiency up to 5.8%.

6-(D-2-[4-hydroxy-1,5-naphthyridine-3-carboxamido]-2-[4-hydroxyphenyl]acetamido)-2,2-dimethyl-3-(5-tetrazolyl)penam

6-(D-2-[4-Hydroxy-1,5-naphthyridine-3-carboxamido]-2-[4-hydroxyphenyl]acetamido-2,2-dimethyl-3-(5-tetrazolyl)penam and the salts thereof are valuable antibacterial agents, particularly for the control of bacterial infections in mammals, especially man.