4906-28-9

Usage

Uses

Used in Pharmaceutical Synthesis:
4-Butoxy-3-nitrobenzoic acid is used as an intermediate in the synthesis of various pharmaceuticals for its versatile chemical structure, which can be modified to create a range of medicinal compounds.
Used in Agrochemical Production:
In the agrochemical industry, 4-Butoxy-3-nitrobenzoic acid is utilized as a precursor in the development of pesticides and other crop protection agents, contributing to its effectiveness in agricultural applications.
Used as an Anti-inflammatory Agent:
4-Butoxy-3-nitrobenzoic acid is used as an anti-inflammatory agent for its potential to reduce inflammation, making it a candidate for treatments involving conditions that benefit from reduced swelling and discomfort.
Used as an Analgesic Agent:
4-Butoxy-3-nitrobenzoic acid is also used as an analgesic agent, helping to alleviate pain due to its capacity to interact with pain receptors and provide relief from discomfort or distress.

InChI:InChI=1/C11H13NO5/c1-2-3-6-17-10-5-4-8(11(13)14)7-9(10)12(15)16/h4-5,7H,2-3,6H2,1H3,(H,13,14)

Upstream product

• 778-28-9 butyl para-toluenesulfonate 
• 616-82-0 3-nitro-4-hydroxybenzoic acid 
• 19013-10-6 ethyl 4-hydroxy-3-nitrobenzoate 

Relevant academic research and scientific papers

N-(3-nitro-4-alkoxybenzoyl)amino acid compounds as well as preparation method and application thereof

The invention discloses N-(3-nitro-4-alkoxybenzoyl)amino acid compounds as well as a preparation method and an application thereof and belongs to the field of medicines. 4-hydroxy-3-nitrobenzoic acidis subjected to methanol esterification, bromo-alkane substitution, hydrolysis and chlorination and then acylated with L-phenylglycine, R2 which is L-phenylglycine sodium salt is obtained, and the N-(3-nitro-4-alkoxybenzoyl)amino acid compounds are obtained after hydrolysis. The N-(3-nitro-4-alkoxybenzoyl)amino acid compounds have novel chemical structures, have good effects in an in-vitro xanthine oxidase inhibition activity test and can be used for treating and preventing gout diseases.

PROCESS FOR PRODUCING 3-NITRO-4-ALKOXYBENZOIC ACID

The present invention provides a process for preparing 3-nitro-4-alkoxybenzoic acid, which comprises the step of subjecting a mixture comprising 4-alkoxybenzoic acid and 40-80% nitric acid, wherein the amount of the 40-80% nitric acid is equal to or more than 8 times that of 4-alkoxybenzoic acid by weight, to a reaction at a temperature of 30-100°C.

Substituted N-aryl heterocycles, process for their preparation and their use as medicaments

The invention relates to substituted N-aryl heterocycles and to the physiologically tolerated salts and physiologically functional derivatives thereof. Compounds of the formula I in which the radicals have the stated meanings, the N-oxides and the physiologically tolerated salts thereof and process for the preparation thereof are described. The compounds are suitable for example as anorectic agents.

Columnar mesophase in a novel series of banana-shaped compounds consisting of functional nitro groups

A novel series of banana-shaped compounds with the following molecular structure has been synthesized and characterized. All the compounds synthesized in this series are found to be liquid crystalline forming a B1 phase, which has recently been designated as a columnar phase. The liquid crystalline behaviour of these compounds has been investigated by using the polarizing optical microscopy, differential scanning calorimetry and x-ray studies. The lower homologues of this series are monotropic whereas the higher ones are enantiotropic. We found that introduction of the nitro functional groups affects the mesomorphic properties in comparison to their respective unsubstituted compounds. The lower homologues of the unsubstituted ones exhibit a B1 phase whereas the higher ones a B2 phase.