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4H-quinolizin-4-one, also known as 4H-1,2,4a,5,6,11b-hexahydro-4aH-quinolizin-4-one, is a heterocyclic compound with the molecular formula C8H7NO. It is a white crystalline solid that is soluble in organic solvents such as ethanol and methanol. 4H-quinolizin-4-one is an important intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. It is also used as a building block in the preparation of complex organic molecules due to its unique structure and reactivity. The compound is synthesized through various methods, including the condensation of 2-aminopyridine with ketones or aldehydes, and it exhibits interesting chemical properties, such as tautomerism and the ability to form complexes with metal ions.

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  • 491-42-9 Structure
  • Basic information

    1. Product Name: 4H-quinolizin-4-one
    2. Synonyms:
    3. CAS NO:491-42-9
    4. Molecular Formula: C9H7NO
    5. Molecular Weight: 145.158
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 491-42-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 376.1°C at 760 mmHg
    3. Flash Point: 192.6°C
    4. Appearance: N/A
    5. Density: 1.24g/cm3
    6. Vapor Pressure: 7.44E-06mmHg at 25°C
    7. Refractive Index: 1.658
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 4H-quinolizin-4-one(CAS DataBase Reference)
    11. NIST Chemistry Reference: 4H-quinolizin-4-one(491-42-9)
    12. EPA Substance Registry System: 4H-quinolizin-4-one(491-42-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 491-42-9(Hazardous Substances Data)

491-42-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 491-42-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,9 and 1 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 491-42:
(5*4)+(4*9)+(3*1)+(2*4)+(1*2)=69
69 % 10 = 9
So 491-42-9 is a valid CAS Registry Number.

491-42-9Downstream Products

491-42-9Relevant articles and documents

HETEROCYCLIC SYNTHESIS BY ELECTROCYCLIZATION OF EXTENDED DIPOLES: A NOVEL ACCESS TO THE INDOLIZINE AND QUINOLIZINE SYSTEMS

Eberbach, Wolfgang,Maier, Wolfram

, p. 5591 - 5594 (2007/10/02)

On thermal activation α-butenynyl substituted pyridine-N-oxides 4 undergo a multistep rearrangement affording 4-oxo-4H-quinolizines (8) and 2-acylindolizines (9).In the geometrical isomeriziation of E-4 to Z-4 annulated isoxazolidines (7) are involved as unstable intermediates.

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