4917-76-4

Basic information

• Product Name: THIODISUCCINIC ACID
• Synonyms: 2,2’-thiobis-butanedioicaci;Butanedioic acid, 2,2'-thiobis-;2,2'-thiodisuccinic acid;ThiodisuccinicAcid,~99%;Thiodisuccinicacid,98+%;2,2'-Thiobis(butanedioic acid);2,2'-Thiobissuccinic acid;2-(1,4-dihydroxy-1,4-dioxo-butan-2-yl)sulfanylbutanedioic acid
• CAS NO: 4917-76-4
• Molecular Formula: C₈H₁₀O₈S
• Molecular Weight: 266.23
• EINECS: 225-544-8
• Mol File: 4917-76-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 196-197°C
• Boiling Point: 456.2 °C at 760 mmHg
• Flash Point: 229.7 °C
• Appearance: /
• Density: 1.73 g/cm³
• Refractive Index: 1.659
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.01±0.23(Predicted)
• BRN: 1804352
• CAS DataBase Reference: THIODISUCCINIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: THIODISUCCINIC ACID(4917-76-4)
• EPA Substance Registry System: THIODISUCCINIC ACID(4917-76-4)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• TSCA: Yes
• Hazardous Substances Data: 4917-76-4(Hazardous Substances Data)

Usage

Description

Thiodisuccinic acid is a chemical compound derived from succinic acid, where the oxygen atoms are replaced with sulfur atoms. It exhibits chelating properties, enabling it to bind with metal ions and form stable complexes. This unique characteristic positions it as a versatile agent in various industrial and medical applications.

Uses

Used in Industrial Applications:
Thiodisuccinic acid is used as a chelating agent for its ability to bind metal ions, which is beneficial in applications such as metal cleaning products, corrosion inhibition, and as a stabilizer in metal plating processes. Its effectiveness in these areas stems from its capacity to form stable complexes with metal ions, enhancing the performance and longevity of metal-related products and processes.
Used in Personal Care Products:
In the personal care industry, Thiodisuccinic acid is utilized as a component in shampoos and conditioners. It serves to improve the stability and appearance of these products, ensuring they maintain their quality and effectiveness over time.
Used in Medical Applications:
Thiodisuccinic acid is being explored in the medical field for its potential to enhance the targeted delivery of certain drugs to specific tissues in the body. Its chelating properties could improve drug distribution and effectiveness, offering new possibilities for treatment strategies in medicine.

InChI:InChI=1/C7H5FN2/c8-6-2-4-10-7-5(6)1-3-9-7/h1-4H,(H,9,10)

Upstream product

• 70-49-5 DL-thiomalic acid 
• 110-16-7 maleic acid 
• 108-31-6 maleic anhydride 

Relevant articles and documents

Direct NMR detection of the unstable "red product" from the reaction between nitroprusside and 2-mercaptosuccinic acid

The reaction between nitroprusside (NP, [FeII(CN)5NO]2-) and organic thiolates (RS-) in aqueous solution has long been known to produce an unstable red intermediate thus often being referred to as the "red product" (RP) in the literature. While RP has always been formulated as [FeII(CN)5N(O)SR]3-, it is rather difficult to study it in aqueous solution because it is not only unstable but also exhibits rapid ligand exchange. All previous studies of RP have relied on UV-vis, IR, kinetics measurements, and analysis of decomposed products. Herein we report the first comprehensive multinuclear (1H, 13C, 15N, and 17O) NMR characterization of the RP produced from the reaction between NP and 2-mercaptosuccinic acid (MSA). The NMR chemical shifts obtained for the RP are compared with those from the free ligand (S-nitrosothiol, RS-NO) prepared in situ by the reaction of MSA with NaNO2. We also showed that useful thermodynamic and kinetic properties of RP formation can be readily obtained from 1H NMR studies.

A magnetically retrievable heterogeneous copper nanocatalyst for the synthesis of 5-substituted tetrazoles and oxidation reactions

Abstract: A copper complex anchored on functionalized Fe3O4 nanoparticles was prepared by a simple and inexpensive procedure using commercially available materials. The prepared catalyst was characterized by a range of physical and spectroscopic techniques. Ease of operation, high efficiency, eco-friendly procedure, easy separation of the catalyst and reusability for several consecutive runs without significant loss of its activity are several advantages of this catalyst. The catalytic activity has been explored for the oxidation of sulfides, oxidative coupling of thiols and synthesis of 5-substituted tetrazoles. Graphical Abstract: A magnetically retrievable heterogeneous copper nanocatalyst for the synthesis of 5-substituted tetrazoles and oxidation reactions[Figure not available: see fulltext.].