491837-23-1

Basic information

• Product Name: Thymidine, 5'-S-[bis(4-methoxyphenyl)phenylmethyl]-3'-S-methyl-3',5'-dithio-
• CAS NO: 491837-23-1
• Molecular Formula: C32H34N2O5S2
• Molecular Weight: 590.764
• Mol File: 491837-23-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Thymidine, 5'-S-[bis(4-methoxyphenyl)phenylmethyl]-3'-S-methyl-3',5'-dithio-(CAS DataBase Reference)
• NIST Chemistry Reference: Thymidine, 5'-S-[bis(4-methoxyphenyl)phenylmethyl]-3'-S-methyl-3',5'-dithio-(491837-23-1)
• EPA Substance Registry System: Thymidine, 5'-S-[bis(4-methoxyphenyl)phenylmethyl]-3'-S-methyl-3',5'-dithio-(491837-23-1)

Safety Data

• Hazardous Substances Data: 491837-23-1(Hazardous Substances Data)

Upstream product

• 491837-22-0 5'-S-(4,4'-dimethoxytrityl)-3',5'-dithiothymidine 
• 74-88-4 methyl iodide 
• 183428-15-1 1-[(2R,4S,5R)-4-(4-Methoxy-benzylsulfanyl)-5-(4-methoxy-benzylsulfanylmethyl)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 183428-19-5 3',5'-dithiothymidine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 

Relevant articles and documents

Artificial nucleosides possessing metal binding sites at the 3′- and 5′-positions of the deoxyribose moieties

This paper describes a convenient synthetic procedure for nucleoside mimics, 1-6, in which the 3′,5′-hydroxy groups of natural 2′-deoxythymidine or 2′-deoxyadenosine are replaced by thiol, amine, or alkylthiol groups. Such nucleosides would be built up into a single DNA strand with cooperative participation of metal coordination, where internucleoside linkages are replaced by metal complexation motifs. The X-ray crystal structure and complexation behaviors of 3′,5′-dithiothymidine, 1, with AuI are also reported.