491856-79-2

Basic information

• Product Name: 6-methyl-2-(3-nitrophenyl)imidazo[1,2-a]pyridine
• Synonyms: 6-methyl-2-(3-nitrophenyl)imidazo[1,2-a]pyridine
• CAS NO: 491856-79-2
• Molecular Weight: 253.26
• Mol File: 491856-79-2.mol

Chemical Properties

• CAS DataBase Reference: 6-methyl-2-(3-nitrophenyl)imidazo[1,2-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-2-(3-nitrophenyl)imidazo[1,2-a]pyridine(491856-79-2)
• EPA Substance Registry System: 6-methyl-2-(3-nitrophenyl)imidazo[1,2-a]pyridine(491856-79-2)

Safety Data

• Hazardous Substances Data: 491856-79-2(Hazardous Substances Data)

Upstream product

• 1603-41-4 (5-methyl-pyridin-2-yl)amine 
• 121-89-1 3-Nitroacetophenone 

Downstream Products

• 1228303-17-0 [6-methyl-2-(3-nitrophenyl)imidazo[1,2-a]pyridin-3-yl]methanol 

Relevant articles and documents

Copper catalyzed tandem oxidative C-H amination/cyclizations: Direct access to imidazo[1,2-a]pyridines

A simple and convenient strategy is described for the synthesis of imidazo[1,2-a]pyridines via inexpensive copper-catalyzed tandem imine formation and intramolecular aerobic oxidative C-H bond amination/cyclizations. An array of imidazo[1,2-a]pyridines were prepared by the reaction of readily available acetophenones and 2-aminopyridines in good to excellent yields (48-92%). The scope of the method was validated by a single step synthesis of Zolimidine, a drug used for peptic ulcers, in 61% yield. The Royal Society of Chemistry 2013.

Application of Imidazopyridine Derivatives in Regenerative Medicine

A method of producing a pluripotent stem cell is provided. The method is comprising contacting a non-pluripotent donor cell obtained from a mammalian donor with a compound characterized by general formulas (1) and (3). Furthermore, methods for inducing OCT4 and NANOG, increasing histone 3 lysine methylation and the maintenance of pluripotency are provided.