492435-29-7Relevant academic research and scientific papers
Stereoselective formation of optically active 2-oxy-1,3-oxazolidin-4-ones and an efficient synthesis of optically active secondary 2-pyrrolidones
Omata, Yoji,Kakehi, Akikazu,Shirai, Masashi,Kamimura, Akio
, p. 6911 - 6914 (2007/10/03)
Treatment of (-)-O-acyllactamides or mandelamides with TBSOTf in the presence of base gives optically active 2-oxy-1,3-oxazolidin-4-ones stereoselectively, which serve as useful precursors for the preparation of optically active secondary 2-pyrrolidones via radical cyclization and subsequent one-step removal of mandelic acid.
