492439-30-2Relevant academic research and scientific papers
Synthesis and cyclic AMP phosphodiesterase 4 isoenzyme inhibitory activity of heterocycle condensed purines.
Suzuki, Hirokazu,Yamamoto, Manabu,Shimura, Susumu,Miyamoto, Ken-ichi,Yamamoto, Kenji,Sawanishi, Hiroyuki
, p. 1163 - 1168 (2002)
To reverse the adverse reactions of alkylxanthines and to develop novel inhibitors of cyclic AMP phosphodiesterase 4 (PDE4), a series of heterocycle [a]-, [b]-, [c,d]-, and [i]-condensed purines were designed and synthesized. Although all compounds did no
