492472-24-9Relevant academic research and scientific papers
Synthesis and cytotoxic activity of carboxamide derivatives of benzo[b][1,6]naphthyridines
Deady, Leslie W.,Rodemann, Thomas,Zhuang, Li,Baguley, Bruce C.,Denny, William A.
, p. 1049 - 1054 (2003)
The reaction of 4-dimethylaminomethylene-6-methyl-4H-pyrano[4,3-b] quinoline-1,3-dione with a range of primary amines gave rise to a series of 2-substituted 6-methyl-1-oxo-1,2-dihydrobenzo-[b] [1,6]naphthyridine-4-carboxylic acids. The derived 4-N-[2-(dim
ANTI-TUMOUR POLYCYCLIC CARBOXAMIDES
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Page/Page column 32-33, (2008/06/13)
This invention relates to polycyclic carboxamide compounds of the formula (I) with cytotoxicity, processes for their preparation, pharmaceutical compositions containing them and their use in therapy, particularly in the treatment and/or prophylaxis of cellular proliferative disorders such as cancer.
