4927-26-8 Usage
Uses
Used in Hormonal Birth Control:
3beta,17-dihydroxy-16alpha-methylpregn-5-en-20-one is used as a contraceptive agent in hormonal birth control methods, such as the contraceptive pill. It functions by mimicking the effects of natural progesterone, thereby helping to regulate the menstrual cycle and prevent ovulation, which reduces the likelihood of pregnancy.
Used in the Treatment of Menstrual Disorders:
In the healthcare industry, 3beta,17-dihydroxy-16alpha-methylpregn-5-en-20-one is used as a therapeutic agent for the treatment of certain menstrual disorders. It aids in stabilizing the menstrual cycle and alleviating symptoms associated with hormonal imbalances.
Used in Endometriosis Treatment:
3beta,17-dihydroxy-16alpha-methylpregn-5-en-20-one is utilized as a medical treatment for endometriosis, a condition where the tissue that lines the uterus grows outside of it. This synthetic hormone helps to manage the symptoms and reduce the progression of the disease.
Used in Hormone Replacement Therapy:
In the field of menopause management, 3beta,17-dihydroxy-16alpha-methylpregn-5-en-20-one is used as a component of hormone replacement therapy. It is administered to alleviate menopausal symptoms by providing the body with the necessary hormones to counteract the effects of decreased natural production during menopause.
Administered through Oral or Injectable Forms:
3beta,17-dihydroxy-16alpha-methylpregn-5-en-20-one can be administered orally or through injection, allowing for flexible treatment options that cater to individual patient needs and preferences.
Check Digit Verification of cas no
The CAS Registry Mumber 4927-26-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,9,2 and 7 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4927-26:
(6*4)+(5*9)+(4*2)+(3*7)+(2*2)+(1*6)=108
108 % 10 = 8
So 4927-26-8 is a valid CAS Registry Number.
4927-26-8Relevant academic research and scientific papers
Autooxidation of Δ17(20)-20-hydroxy derivatives of steroids. Synthesis of 3β-acetoxy-17α-hydroperoxy-16α- methylpregn-5-en-20-one and its reduction to 17α-hydroxy derivative
Savinova,Lukashev,Huy,Beletskaya
experimental part, p. 54 - 61 (2011/04/27)
An efficient procedure was proposed for the synthesis of 3β-acetoxy-17α-hydroperoxy-16α-methylpregn-5-en-20-one. Optimal conditions were found for the combined process including 1,4-addition of methylmagnesium bromide at the Δ16-20-oxo fragment of dehydropregnenolone acetate and autooxidation of resulting bromomagnesium 3β-acetoxy-16α-methylpregna-5,17(20)-dien-20-olate. The subsequent reduction of the 17α-hydroperoxy group and hydrolysis of the 3β-acetoxy group afforded 17α-hydroxy-16α-methyl-substituted dehydropregnenolone acetate and its 3-hydroxy analog in high yield.
Efficient synthesis of 16α-methyl cyproterone acetate
Sakee, Uthai,Kongkathip, Boonsong,Kongkathip, Ngampong
, p. 12 - 13 (2007/10/03)
An effective method for synthesis of 16α-methyl cyproterone acetate was accomplished starting from commercially available 16-dehydropregnenolone acetate in eight steps, 11.5% overall yield.
