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Usage

Uses

Used in Pharmaceutical Industry:
2,3-DIBROMOBENZOTRIFLUORIDE is used as a solvent and intermediate for the synthesis of various pharmaceutical compounds. Its chemical stability and solubility properties make it suitable for use in the production of drugs that require specific reaction conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 2,3-DIBROMOBENZOTRIFLUORIDE serves as an intermediate in the production of pesticides and other agricultural chemicals. Its stability and reactivity contribute to the development of effective and long-lasting agrochemical products.
Used in Industrial Chemical Processes:
2,3-DIBROMOBENZOTRIFLUORIDE is utilized in various industrial chemical processes due to its high thermal and chemical stability. It can be employed in the synthesis of a range of industrial products, including polymers, dyes, and other specialty chemicals.
Used in Environmental Management:
Although 2,3-DIBROMOBENZOTRIFLUORIDE has been identified as a potential environmental contaminant, its properties are also leveraged in environmental management strategies. Proper handling, storage, and disposal methods are crucial to mitigate its potential impact on the environment and human health.

Upstream product

• 392-83-6 o-trifluoromethylphenyl bromide 
• 367-67-9 2-bromo-5-nitro-benzotrifluoride 

Downstream Products

• 865352-01-8 2-(2',2'-difluoroethoxy)-6-trifluoromethylbenzene-1-sulfonyl chloride 

Relevant academic research and scientific papers

Synthesis method of 2-(2, 2-difluoroethyoxyl)-6-trifluoromethyl benzenesulfonyl chloride

The invention discloses a synthesis method of 2-(2, 2-difluoroethyoxyl)-6-trifluoromethyl benzenesulfonyl chloride. The preparation method comprises the following steps: dissolving 2-trifluoromethyl-4-nitro-bromobenzene in sulfuric acid, adding a halogenating reagent, and reacting at 50-100 DEG C for 1-8 hours; dissolving the obtained 2-bromo-3-trifluoromethyl-5-nitro-benzene halide in a solvent, and performing reduction in a reduction system; carrying out diazotization on the obtained 3-halo-4-bromo-5-trifluoromethyl-aniline, and then carrying out decomposition on the obtained 3-halo-4-bromo-5-trifluoromethyl-aniline; carrying out Grignard reaction on the obtained 2-bromo-3-trifluoromethyl-benzene halide, and then reacting with dialkyl disulfide; carrying out etherification reaction on the obtained 2-alkylthio-3-trifluorotoluene-benzene halide and 2, 2-difluoroethanol in an organic solvent under the action of an alkali; and reacting the obtained 2-(2, 2-difluoroethoxy)-6-trifluoromethyl-phenylalkyl sulfide with chlorine gas at 10-60 DEG C for 1-5 hours. The method is short in route, mild in condition, high in yield and suitable for industrial production.

An improved method for the bromination of metalated haloarenes via lithium, zinc transmetalation: A convenient synthesis of 1,2-dibromoarenes

A facile protocol for the synthesis of 1,2-dibromoarenes is described. A standard ortho-lithiation/bromination procedure, when applied to bromoarenes, resulted in poor yields of the corresponding 1,2-dibromoarenes (13-62% yield). However, transmetalation