4931-10-6Relevant academic research and scientific papers
The dearomative annulation between N -2-pyridylamidine and CO2 toward pyrido[1,2-a]-1,3,5-triazin-4-ones
Xia, Minfang,Hu, Weiming,Sun, Song,Yu, Jin-Tao,Cheng, Jiang
supporting information, p. 4064 - 4067 (2017/07/10)
A base-promoted dearomative annulation between N-2-pyridylamidine and an atmospheric pressure of CO2 was developed, affording a series of pyrido[1,2-a]-1,3,5-triazin-4-ones in moderate to excellent yields. CO2 served as a carbonyl so
I2/KI-Mediated Oxidative N-N Bond Formation for the Synthesis of 1,5-Fused 1,2,4-Triazoles from N -Aryl Amidines
Song, Lina,Tian, Xianhai,Lv, Zhigang,Li, Ertong,Wu, Jie,Liu, Yangxue,Yu, Wenquan,Chang, Junbiao
, p. 7219 - 7225 (2015/07/28)
An I2/KI-mediated oxidative N-N bond formation reaction is described. This new and environmentally benign approach allows for the convenient synthesis of a variety of 1,2,4-triazolo[1,5-a]pyridines and other 1,5-fused 1,2,4-triazoles from readi
PhI(OCOCF3)2-mediated intramolecular oxidative N-N bond formation: Metal-free synthesis of 1,2,4-triazolo[1,5-a]pyridines
Zheng, Zisheng,Ma, Shuangyu,Tang, Linlin,Zhang-Negrerie, Daisy,Du, Yunfei,Zhao, Kang
, p. 4687 - 4693 (2014/06/09)
The biologically important 1,2,4-triazolo[1,5-a]pyridines were readily synthesized from N-(pyridin-2-yl)benzimidamides via phenyliodine bis(trifluoroacetate)-mediated intramolecular annulation. This novel strategy allows for the convenient construction of a 1,2,4-triazolo[1,5-a]pyridine skeleton through direct metal-free oxidative N-N bond formation, featuring a short reaction time and high reaction yields.
