4931-36-6Relevant academic research and scientific papers
IMIDAZOTRIAZINONE COMPOUNDS
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Paragraph 0750; 0751, (2013/10/08)
The present invention provides imidazotriazinone compounds which are inhibitors of phosphodiesterase 9 and pharmaceutically acceptable salt thereof. The present invention further provides processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of PDE9 associated diseases or disorders in mammals, including humans.
NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A
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, (2013/02/28)
The present invention relates to novel carboxamide compounds, pharmaceutical compositions containing them, and their use in therapy. The compounds possess valuable therapeutic properties and are particularly suitable for treating or controlling medical disorders selected from neurological disorders and psychiatric disorders, for ameliorating the symptoms associated with such disorders and for reducing the risk of such disorders
Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of gonadotropin releasing hormone receptor
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Page/Page column 29; 41-42, (2008/06/13)
The present invention relates to Gonadotropin Releasing Hormone (GnRH, also known as Luteinizing Hormone Releasing Hormone) receptor antagonists.
Synthesis of Triazaphospholopyridines(1+)
Bansal, Raj K.,Gandhi, Neelam,Schmidpeter, A.,Karaghiosoff, K.
, p. 558 - 562 (2007/10/02)
Condensation of 1,2-diaminopyridinium iodides with tris(dimethylamino)phosphine gives triazaphospholopyridines 2a-d.Diethylamine adds to the N=P bond of 2a,b only if the phosphorus is oxidized at the same time.Hydrolysis of 2a opens the triazaphosphole ring at its 2,3-bond. - Keywords: 1,3-Diaza-2-phosphaindolizines, NMR Spectra, Mass Spectral Fragmentation, Hydrolysis, 1,2-Addition Reactions
