Phosphohistidine is a phosphorylated derivative of the amino acid histidine, which plays a crucial role in various biological processes. It is formed when a phosphate group is attached to the imidazole ring of histidine, resulting in a negatively charged molecule. Phosphohistidine is involved in enzyme regulation, signal transduction, and energy transfer within cells. It is particularly important in the function of certain enzymes, such as alkaline phosphatase and ATPases, where it can modulate their activity. Additionally, phosphohistidine has been implicated in the regulation of protein-protein interactions and serves as a potential biomarker for certain diseases. Understanding the role of phosphohistidine in cellular processes is essential for comprehending the intricate mechanisms of protein phosphorylation and its impact on cellular function.
4936-08-7
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Basic information
- Product Name: phosphohistidine
- Synonyms: phosphohistidine
- CAS NO:4936-08-7
- Molecular Formula: C6H10N3O5P
- Molecular Weight: 235.13
- EINECS: N/A
- Product Categories: N/A
- Mol File: 4936-08-7.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 689°C at 760 mmHg
- Flash Point: 370.5°C
- Appearance: /
- Density: 1.764g/cm3
- Vapor Pressure: 6.21E-20mmHg at 25°C
- Refractive Index: 1.64
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 2.13±0.10(Predicted)
- CAS DataBase Reference: phosphohistidine(CAS DataBase Reference)
- NIST Chemistry Reference: phosphohistidine(4936-08-7)
- EPA Substance Registry System: phosphohistidine(4936-08-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 4936-08-7(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 4936-08-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,9,3 and 6 respectively; the second part has 2 digits, 0 and 8 respectively.Calculate Digit Verification of CAS Registry Number 4936-08:
(6*4)+(5*9)+(4*3)+(3*6)+(2*0)+(1*8)=107
107 % 10 = 7
So 4936-08-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H10N3O5P/c10-6(11)5(9-15(12,13)14)1-4-2-7-3-8-4/h2-3,5H,1H2,(H,7,8)(H,10,11)(H3,9,12,13,14)/t5-/m0/s1
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phosphohistidine
