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9,13-bis-demethylretinol is a naturally occurring retinoid, which is a derivative of vitamin A. It is characterized by the absence of two methyl groups at the 9th and 13th carbon positions in its molecular structure, distinguishing it from other retinoids. 9,13-bis-demethylretinol plays a significant role in various biological processes, including cell growth, differentiation, and vision. 9,13-bis-demethylretinol has been found to exhibit potential anti-cancer properties, as it can induce cell differentiation and apoptosis in certain cancer cell lines. Additionally, it has been implicated in the regulation of the immune system and the maintenance of skin health. Due to its unique structure and biological activities, 9,13-bis-demethylretinol is a subject of ongoing research to better understand its potential therapeutic applications and mechanisms of action.

4939-51-9

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4939-51-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4939-51-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,9,3 and 9 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 4939-51:
(6*4)+(5*9)+(4*3)+(3*9)+(2*5)+(1*1)=119
119 % 10 = 9
So 4939-51-9 is a valid CAS Registry Number.

4939-51-9Relevant academic research and scientific papers

The Suzuki Reaction in Stereocontrolled Polyene Synthesis: Retinol (Vitamin A), its 9- and/or 13-Demethyl Analogs, and Related 9-Demethyl-dihydroretinoids

Torrado, Alicia,Iglesias, Beatriz,Lopez, Susana,Lera, Angel R. de

, p. 2435 - 2454 (2007/10/02)

A new synthesis of retinol (vitamin A) and 9- and/or 13-demethylretinols, with essentially complete control of regio- and stereochemistry, is described which is based on the thallium-accelerated, palladium-catalyzed cross-coupling reactions of (E)-1-alkenylboronic acids and (E)-1-alkenyl iodides (Suzuki reaction).The procedure has also been extended to the stereocontrolled synthesis of a series of 9-demethyl-dihydroretinoids of potential biological interest.

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