494-23-5

Basic information

• Product Name: (2S,5R)-5-(3-Furyl)-2-(2-oxo-4-methylpentyl)-2-methyltetrahydrofuran
• Synonyms: (+)-1-[(2S,5R)-5-(3-Furyl)-2-methyl-2,3,4,5-tetrahydrofuran-2-yl]-4-methyl-2-pentanone;(+)-Nagione;(2S,5R)-5-(3-Furyl)-2-(2-oxo-4-methylpentyl)-2-methyltetrahydrofuran;Ipomeamaron;(2S,5R)-(+)-1-(5-(3-Furyl)tetrahydro-2-methyl-2-furyl)-4-methyl-2-pentanone;2-Pentanone, 1-(5-(3-furyl)tetrahydro-2-methyl-2-furyl)-4-methyl-, (2S,5R)-(+)-;2-Pentanone, 4-methyl-1-(2,3,4,5-tetrahydro-5-methyl(2,3'-bifuran)-5-yl)-, (2R-cis)- (9ci);Nsc 256944
• CAS NO: 494-23-5
• Molecular Formula: C₁₅H₂₂O₃
• Molecular Weight: 250.3334
• Mol File: 494-23-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 343.6°Cat760mmHg
• Flash Point: 161.6°C
• Appearance: /
• Density: 1.016g/cm³
• CAS DataBase Reference: (2S,5R)-5-(3-Furyl)-2-(2-oxo-4-methylpentyl)-2-methyltetrahydrofuran(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,5R)-5-(3-Furyl)-2-(2-oxo-4-methylpentyl)-2-methyltetrahydrofuran(494-23-5)
• EPA Substance Registry System: (2S,5R)-5-(3-Furyl)-2-(2-oxo-4-methylpentyl)-2-methyltetrahydrofuran(494-23-5)

Safety Data

• Hazardous Substances Data: 494-23-5(Hazardous Substances Data)

Usage

General Description

The chemical "(2S,5R)-5-(3-Furyl)-2-(2-oxo-4-methylpentyl)-2-methyltetrahydrofuran" is a compound with a complex molecular structure. It consists of a tetrahydrofuran ring, with a furyl group attached at the 5th carbon and a 2-oxo-4-methylpentyl group attached at the 2nd carbon. The stereochemistry of the compound is designated as (2S,5R), indicating the configuration of the chiral centers in the molecule. (2S,5R)-5-(3-Furyl)-2-(2-oxo-4-methylpentyl)-2-methyltetrahydrofuran may have potential applications in pharmaceuticals, flavorings, or other industries due to its unique structural features. However, further research would be needed to determine its specific uses and properties.

Upstream product

• 131317-18-5 5α-(3'-furyl)-2β-(toluenesulfonyl)methoxy-2α-methyloxolane 
• 60007-01-4 bis-1,3-propane dithioketal of 5α-(3'-furyl)-2β-((formyl)methyl)-2α-methyloxolane 
• 100059-30-1 5-Methyl-2,3,4,5-tetrahydro-[2,3']bifuranyl-5-carboxylic acid methyl ester 
• 60122-18-1 5α-(3'-furyl)-2β-(iodomethyl)-2α-methyloxolane 
• 131317-12-9 5α-(3'-furyl)-2β-hydroxymethyl-2α-methyloxolane 
• 60007-02-5 bis-1,3-propane dithioketal of trans-4-methyl-1-(2,3,4,5-tetrahydro-5-methyl<2,3'-bifuran>-5-yl)-2-pentanone 
• 100059-29-8 (5-methyl-2,3,4,5-tetrahydro-[2,3']bifuryl-5-yl)-acetic acid 
• 3431-68-3 diisobutylcadmium 
• 131317-18-5 5α-(3'-furyl)-2α-(toluenesulfonyl)methoxy-2β-methyloxolane 
• 60007-01-4 bis-1,3-propane dithioketal of 5α-(3'-furyl)-2α-((formyl)methyl)-2β-methyloxolane 
• 60122-18-1 5α-(3'-furyl)-2α-(iodomethyl)-2β-methyloxolane 
• 131317-12-9 5α-(3'-furyl)-2α-hydroxymethyl-2β-methyloxolane 
• 60007-02-5 bis-1,3-propane dithioketal of cis-4-methyl-1-(2,3,4,5-tetrahydro-5-methyl<2,3'-bifuran>-5-yl)-2-pentanone 
• 51703-95-8 9-acetoxy-9-[3]furyl-2,6-dimethyl-non-5ξ-en-4-one 

Relevant articles and documents

Formal Total Synthesis of Ipomeamarone via the Dihydrofuran Annulation

A formal synthesis of (2R-cis)-4-methyl-1-(2,3,4,5-tetrahydro)-5-methyl--2-pentanone, or ipomeamarone (1) was accomplished from 3-furaldehyde 5 and ethyl-2-bromocrotonate 4.The key step involved the formation of the dihydrofuran ring in 2 via a vinyloxirane rearrangement of 3 in the dihydrofuran annulation.Mechanistic duality of reactions of those tetrahydrofurans possessing acidic hydrogens adjacent to the ring is addressed.