494205-62-8

Upstream product

• 122948-53-2 [2-(4-bromophenyl)prop-2-enyl]trimethylsilane 
• 494205-60-6 {4-[(dimethoxymethyl)phenyl]}(methoxy)dimethylsilane 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 494205-61-7 2-(4-bromo-phenyl)-1,3-bis-trimethylsilanyl-propan-2-ol 
• 24856-58-4 1,1-dimethoxy-1-(4-bromophenyl)methane 

Downstream Products

• 445399-06-4 4-[4-({1-[(trimethylsilyl)methyl]ethenyl}phenyl)dimethylsilyl]benzaldehyde 

Relevant academic research and scientific papers

Asymmetric polymer synthesis by repetitive Sakurai-Hosomi allylation reaction of compounds possessing both formyl and allylsilane functions

Trialkylallylsilanes generally react with aldehydes in the presence of a Lewis acid to the corresponding homoallylic alcohols. Chiral Lewis acids promote the same reaction to yield the enantiomerically-enriched homoallylalcohols. We have prepared four compounds (7-10) that possess both formyl and allylsilane functions. Lewis acids initiated self-polyaddition reactions of these compounds by means of repetitive allylation. The use of chiral Lewis acids resulted in the formation of optically active polymers that possess exo-methylene and secondary OH functions in their main chain. The optical purity of these chiral polymers was estimated based on the results of model asymmetric reactions between benzaldehyde and β-substituted allylsilanes and by controlled degradation.

Asymmetric synthesis of chiral polymers by means of repetitive addition of allylsilane to aldehyde

Monomers having both allyltrimethylsilyl and formyl groups were prepared. Chiral (acyloxy)borane initiated the repetitive polyaddition of the monomers to give optically active polymers having main chain configurational chirality. Optical purity of the chiral polymer was evaluated by the analysis of the degradation product.