4947-29-9Relevant academic research and scientific papers
On the Elimination of the 3-Benzylthioenol Ether of Pregn-4-ene-3,20-dione by W-2 Raney Nickel
Gonzalez, Mario D.,Burton, Gerardo
, p. 639 - 644 (2007/10/02)
Reaction of 3-benzylthiopregna-3,5-dien-20-one or of pregna-3,5-dien-20-one with W-2 Raney nickel in acetone afforded a mixture of 20-ketopregnanes with different degrees of insaturation on rings A and B, of which the main component was identified as pregn-2-en-20-one.When deactivated Raney nickel was used, the main product was the expected pregna-3,5-dien-20-one with minor amounts of pregn-4-en-20-one and pregn-5-en-20-one. - Key words: Benzylthioenol Ether, Raney Nickel, 3-Benzylthiopregna-3,5-dien-20-one, Pregna-3,5-dien-20-one, Pregn-2-en-20-one
