494752-42-0

Basic information

• Product Name: Boronic acid, (4-amino-3-fluorophenyl)- (9CI)
• Synonyms: Boronic acid, (4-amino-3-fluorophenyl)- (9CI);4-Amino-3-fluorophenylboronic acid;3-fluoro-4-aMinobenzene boronic acid
• CAS NO: 494752-42-0
• Molecular Formula: C₆H₇BFNO₂
• Molecular Weight: 191.4
• Product Categories: HALIDE;Organic boronic acid
• Mol File: 494752-42-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.34
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Boronic acid, (4-amino-3-fluorophenyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Boronic acid, (4-amino-3-fluorophenyl)- (9CI)(494752-42-0)
• EPA Substance Registry System: Boronic acid, (4-amino-3-fluorophenyl)- (9CI)(494752-42-0)

Safety Data

• Hazardous Substances Data: 494752-42-0(Hazardous Substances Data)

Usage

Uses

(4-Amino-3-fluorophenyl)boronic Acid is used in preparation of N-(phenyl)benzenesulfonamides as GPR120 agonists for treatment of GPR120-mediated diabetes.

InChI:InChI=1/C6H7BFNO2.ClH/c8-5-3-4(7(10)11)1-2-6(5)9;/h1-3,10-11H,9H2;1H

Upstream product

• 367-24-8 4-bromo-2-fluoroaniline 
• 201733-56-4 2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-5,5-dimethyl-1,3,2-dioxaborinane 

Downstream Products

• 1001608-52-1 C₇H₇BFNO₃ 
• 1383385-24-7 C₂₅H₃₁FN₂O₂S 
• 1132610-14-0 C₃₅H₄₀FN₇O₄ 
• 1001608-50-9 4-amino-3-fluoro-5-iodophenylboronic acid 

Relevant articles and documents

Synthesis and crystal structure of 4-amino-3-fluorophenylboronic acid

4-Amino-3-fluorophenyl boronic acid has been synthesized from 4-bromo-2-fluoroaniline by protecting the amine group and then carrying out a lithium-bromine exchange, followed by addition of trimethyl borate and then acidic hydrolysis. We obtained a 47% yi

INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS

Disclosed are compounds having formula I and related compositions and methods thereof. The compounds are useful for treating viral infections caused by the Flaviviridae family of viruses.