494755-58-7Relevant academic research and scientific papers
A highly cis-selective synthesis of 2-ethynylaziridines by intramolecular amination of chiral bromoallenes: Improvement of stereoselectivity based on the computational investigation
Ohno, Hiroaki,Ando, Kaori,Hamaguchi, Hisao,Takeoka, Yusuke,Tanaka, Tetsuaki
, p. 15255 - 15266 (2002)
The base-mediated intramolecular amination of bromoallenes having an axial chirality is described. The treatment of (4S,aR)-4-alkyl-4-[N-(arylsulfonyl)amino]-1-bromobuta-1,2-dienes with NaH in DMF affords 2,3-cis-2-ethynylaziridines in good to excellent s
