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5-bromo-2-(cyclopropylmethoxy)pyridine is a heterocyclic aromatic compound characterized by its molecular formula C8H8BrNO and a molar mass of 217.06 g/mol. It features a pyridine ring, a bromine atom, and a cyclopropylmethoxy group, which contribute to its unique structure and reactivity. This chemical compound is frequently utilized as a building block in organic synthesis and pharmaceutical research, offering potential in the development of innovative drugs and agrochemicals.

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  • 494772-02-0 Structure
  • Basic information

    1. Product Name: 5-bromo-2-(cyclopropylmethoxy)pyridine
    2. Synonyms: 5-bromo-2-(cyclopropylmethoxy)pyridine
    3. CAS NO:494772-02-0
    4. Molecular Formula: C9H10BrNO
    5. Molecular Weight: 228.088
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 494772-02-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-bromo-2-(cyclopropylmethoxy)pyridine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-bromo-2-(cyclopropylmethoxy)pyridine(494772-02-0)
    11. EPA Substance Registry System: 5-bromo-2-(cyclopropylmethoxy)pyridine(494772-02-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 494772-02-0(Hazardous Substances Data)

494772-02-0 Usage

Uses

Used in Organic Synthesis:
5-bromo-2-(cyclopropylmethoxy)pyridine is used as a key intermediate in organic synthesis for the creation of complex organic molecules. Its cyclopropyl group serves as a valuable synthetic handle, allowing for further functionalization and the development of a diverse range of chemical products.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 5-bromo-2-(cyclopropylmethoxy)pyridine is employed as a building block for the development of new drugs. Its unique structure and reactivity make it a promising candidate for the synthesis of bioactive compounds with potential therapeutic applications.
Used in Agrochemical Development:
5-bromo-2-(cyclopropylmethoxy)pyridine also has potential applications in the agrochemical sector, where it can be used as a starting material for the synthesis of novel agrochemicals with improved efficacy and selectivity.
Overall, 5-bromo-2-(cyclopropylmethoxy)pyridine is a versatile chemical compound with a wide range of applications in various industries, including organic synthesis, pharmaceutical research, and agrochemical development, due to its unique structure, reactivity, and synthetic potential.

Check Digit Verification of cas no

The CAS Registry Mumber 494772-02-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,9,4,7,7 and 2 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 494772-02:
(8*4)+(7*9)+(6*4)+(5*7)+(4*7)+(3*2)+(2*0)+(1*2)=190
190 % 10 = 0
So 494772-02-0 is a valid CAS Registry Number.

494772-02-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Bromo-2-(cyclopropylmethoxy)pyridine

1.2 Other means of identification

Product number -
Other names RW3637

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:494772-02-0 SDS

494772-02-0Relevant articles and documents

INHIBITORS OF TRPC6

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Page/Page column 44; 89; 90, (2019/09/04)

The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts therefore, wherein R1 to R6, A, U, V, W, X, Y, and Z are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

AZETIDINE COMPOUNDS AS GRP119 MODULATORS FOR THE TREATMENT OF DIABETES, OBESITY, DYSLIPIDEMIA AND RELATED DISORDERS

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Paragraph 0236, (2018/09/12)

The present disclosure relates to azetidine compounds. The azetidine compounds are GPR119 modulators and useful for the prevention and/or treatment of diabetes, obesity, dyslipidemia and related disorders. The present disclosure furthermore relates to the use of azetidine compounds as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.

SUBSTITUTED FUSED HETEROCYCLES AS GPR119 MODULATORS FOR THE TREATMENT OF DIABETES, OBESITY, DYSLIPIDEMIA AND RELATED DISORDERS

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Page/Page column 52; 53, (2015/11/17)

The present invention relates to substituted fused heterocyclic compounds. The substituted fused heterocyclic compounds are GPR1 19 modulators and useful for the prevention and/or treatment of diabetes, obesity, dyslipidemia and related disorders. The invention furthermore relates to the use of substituted fused heterocyclic compounds as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.

ISOINDOLINONE COMPOUNDS AS GPR119 MODULATORS FOR THE TREATMENT OF DIABETES, OBESITY, DYSLIPIDEMIA AND RELATED DISORDERS

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Page/Page column 67; 68, (2015/11/02)

The present invention relates to isoindolinone compounds. The isoindolinone compounds are GPR119 modulators and useful for the prevention and/or treatment of diabetes, obesity, dyslipidemia and related disorders. The invention furthermore relates to the u

SUBSTITUTED INDANONE COMPOUNDS AS GPR119 MODULATORS FOR THE TREATMENT OF DIABETES, OBESITY, DYSLIPIDEMIA AND RELATED DISORDERS

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Page/Page column 44, (2015/11/17)

The present invention relates to indanone compounds. The indanone compounds are GPR119 modulators and useful for the prevention and/or treatment of diabetes, obesity, dyslipidemia and related disorders. The invention furthermore relates to the use of inda

PYRROLIDINONE DERIVATIVES AS GPR119 MODULATORS FOR THE TREATMENT OF DIABETES, OBESITY, DYSLIPIDEMIA AND RELATED DISORDERS

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Paragraph 0282; 0283, (2014/04/18)

The present invention relates to pyrrolidinone derivatives. The pyrrolidinone derivatives are GPR119 modulators and useful for the prevention and/or treatment of diabetes, obesity, dyslipidemia and related disorders. The invention furthermore relates to t

PYRROLIDINONE DERIVATIVES AS GPR119 MODULATORS FOR THE TREATMENT OF DIABETES, OBESITY, DYSLIPIDEMIA AND RELATED DISORDERS

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Page/Page column 45; 46, (2014/05/07)

The present invention relates to pyrrolidinone derivatives of formula (I). The pyrrolidinone derivatives of formula (I) are GPR119 modulators and useful for the prevention and/or treatment of diabetes, obesity, dyslipidemia and related disorders. The invention furthermore relates to the use of pyrrolidinone derivatives as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.

Pyrrolidine derivatives, pharmaceutical compositions and uses thereof

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Paragraph 0458; 0459; 0460; 0461; 0462, (2014/08/07)

The invention relates to new pyrrolidine derivatives of the formula to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.

PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

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Page/Page column 102; 103, (2014/08/07)

The invention relates to new pyrrolidine derivatives of the formula (I), to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.

AZETIDINE DERIVATIVES

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Paragraph 0565; 0566; 0567; 0568; 0569; 0570, (2013/06/28)

Azetidine derivatives of which the following is exemplary and their use in the treatment of obesity, diabetes or dyslipidemia.

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